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Tuberculosis & Respiratory Diseases

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Vol.65 No.5
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식도이완불능증 환자에서 스쿠알렌 복용 후 발생한 지방성 폐렴 1예

A Case of Exogenous Lipoid Pneumonia after Ingestion of Squalene in Patients with Achalasia

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2008, v.65 no.5, pp.421-425
정치영 (대구 파티마병원)
박정철 (대구파티마병원)
이재광 (대구파티마병원)
이유진 (대구파티마병원)
박승찬 (대구파티마병원)
서혜진 (대구 파티마병원)
김연재 (대구 파티마병원)
이병기 (대구 파티마병원)
허동명 (대구 파티마병원)
손경락 (대구파티마병원)
정치영, 박정철, 이재광, 이유진, 박승찬, 서혜진, 김연재, 이병기, 허동명, & 손경락. (2008). 식도이완불능증 환자에서 스쿠알렌 복용 후 발생한 지방성 폐렴 1예. Tuberculosis & Respiratory Diseases, 65(5), 421-425.
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초록

외인성 지방성 폐렴은 지방물질의 흡인에 의하여 발생하는 폐의 만성 염증성 질환으로 임상병력, 방사선학적이상소견과 폐조직에서 지방을 함유한 대식세포를 발견하여 진단할 수 있다. 기여인자로 신경학적 질환, 의식상태의 변화 및 연하장애를 유발하는 위식도 질환들이 있으며, 대부분 보존적 치료를 통해 호전되나 재발을 방지하기 위하여 기여인자에 대한 치료가 필요할 것으로 생각된다.저자들은 식도이완불능증 환자에서 스쿠알렌 복용 후 발생한 지방성 폐렴을 경험하였기에 문헌고찰과 함께 보고하는 바이다.

keywords
Lipoid pneumonia, Achalasia, Squalene

Abstract

Exogenous lipoid pneumonia (ELP) is a chronic inflammatory reaction of the lungs resulting from the aspiration of vegetable, animal or mineral oils. Squalene, is a derivative of shark liver oil that is taken as a traditional remedy in some Asian countries, and is used widely also in cosmetics. Similar to the symptoms in most cases of oil aspiration, the symptoms of squalene-induced lipoid pneumonia are either absent or nonspecific. Hence, the disease is generally detected incidentally. Although many cases with predisposing factors have been reported, ELP with achalasia is quite rare. We report a 47-year old woman with achalasia who developed ELP after ingesting squalene. The patient was treated successfully by supportive care and surgical treatment of the achalasia

keywords
Lipoid pneumonia, Achalasia, Squalene

참고문헌

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Tuberculosis & Respiratory Diseases

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