바로가기메뉴

본문 바로가기 주메뉴 바로가기

Tuberculosis & Respiratory Diseases

Article Contents

Prev Next
e-Submission

Vol.71 No.4
Citation Share

A Case of Common Variable Immune Deficiency Presenting as Recurrent Pneumococcal Pneumonia

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2011, v.71 no.4, pp.282-285
Juhong Jeong (Inha University School of Medicine)



Sung Min Kwak (Inha University School of Medicine)

Juhong, J. , Sung, M. K. , & (2011). A Case of Common Variable Immune Deficiency Presenting as Recurrent Pneumococcal Pneumonia. Tuberculosis & Respiratory Diseases, 71(4), 282-285.
  • Downloaded
  • Viewed
PDF Download

Abstract

Common variable immune deficiency (CVID) is the most common primary immune deficiency, which is manifested as chronic recurrent respiratory infections and hypoglobulinemia. CVID usually presents in the second or third decade of life. A 33-year-old woman was admitted with recurrent pneumococcal pneumonia with bacteremia and had very low levels of serum immunoglobulin G, M and A. This case emphasized a high index of suspiciousness for diagnosis of CVID in a mid-adulthood patient presenting with recurrent pneumonia with hypoglobulinemia.

keywords
Common Variable Immunodeficiency, Pneumonia, Pneumococcal, B-Lymphocytes

Reference

1.

1. Park MA, Li JT, Hagan JB, Maddox DE, Abraham RS. Common variable immunodeficiency: a new look at an old disease. Lancet 2008;372:489-502.

2.

2. Cunningham-Rundles C, Bodian C. Common variable immunodeficiency: clinical and immunological features of 248 patients. Clin Immunol 1999;92:34-48.

3.

3. Bryant A, Calver NC, Toubi E, Webster AD, Farrant J. Classification of patients with common variable immunodeficiency by B cell secretion of IgM and IgG in response to anti-IgM and interleukin-2. Clin Immunol Immunopathol 1990;56:239-48.

4.

4. Primary immunodeficiency diseases. Report of a WHO scientific group. Clin Exp Immunol 1997;109(Suppl 1): 1-28.

5.

5. Conley ME, Notarangelo LD, Etzioni A. Diagnostic criteria for primary immunodeficiencies. Representing PAGID (Pan-American Group for Immunodeficiency) and ESID (European Society for Immunodeficiencies). Clin Immunol 1999;93:190-7.

6.

6. Lee MK, Bae SK, Choi SJ, Park MH, Kim YI. A case of common variable immunodeficiency. Korean J Med 1985;28:273-80.

7.

7. Cho SJ, Kim SH, Lee SJ, Yoo KH, Kim KH. A case of common variable immunodeficiency with fatal measles. J Korean Pediatr Soc 2001;44:1463-8.

8.

8. Oh TH, Lee HC, Lee TY, Song BC, Chung YH, Lee YS, et al. A case of granulomatous hepatitis associated with common variable immunodeficiency. Korean J Hepatol 2001;7:95-9.

9.

9. Bonilla FA, Bernstein IL, Khan DA, Ballas ZK, Chinen J, Frank MM, et al. Practice parameter for the diagnosis and management of primary immunodeficiency. Ann Allergy Asthma Immunol 2005;94(5 Suppl 1):S1-63.

10.

10. Busse PJ, Razvi S, Cunningham-Rundles C. Efficacy of intravenous immunoglobulin in the prevention of pneumonia in patients with common variable immunodeficiency. J Allergy Clin Immunol 2002;109:1001-4.

Tuberculosis & Respiratory Diseases

e-Submission OA Policy