바로가기메뉴

본문 바로가기 주메뉴 바로가기

Tuberculosis & Respiratory Diseases

Article Contents

Prev Next
e-Submission

Vol.74 No.1
Citation Share

A Case of Multicentric Castleman's Disease Presenting with Follicular Bronchiolitis

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2013, v.74 no.1, pp.23-27










& (2013). A Case of Multicentric Castleman's Disease Presenting with Follicular Bronchiolitis. Tuberculosis & Respiratory Diseases, 74(1), 23-27.
  • Downloaded
  • Viewed
PDF Download

Abstract

Multicentric Castleman's disease (CD) is a rare atypical lymphoproliferative disorder, which is characterized by various systemic manifestations. Some patients with multicentric CD may have concomitant lung parenchymal lesions, for which lymphoid interstitial pneumonia (LIP) is known to be the most common pathologic finding. Follicular bronchiolitis and LIP are considered to be on the same spectrum of the disease. We describe a case of multicentric CD with pulmonary involvement, which was pathologically proven as follicular bronchiolitis.

keywords
Bronchiolitis, Lung Diseases, Interstitial, Multi-centric Castleman's Disease

Reference

1.

Ko SF, Hsieh MJ, Ng SH, Lin JW, Wan YL, Lee TY, et al. Imaging spectrum of Castleman's disease. AJR Am J Roentgenol 2004;182:769-75.

2.

Keller AR, Hochholzer L, Castleman B. Hyaline-vascular and plasma-cell types of giant lymph node hyperplasia of the mediastinum and other locations. Cancer 1972;29:670-83.

3.

Castleman B, Iverson L, Menendez VP. Localized mediastinal lymphnode hyperplasia resembling thymoma. Cancer 1956;9:822-30.

4.

Johkoh T, Muller NL, Ichikado K, Nishimoto N, Yoshizaki K, Honda O, et al. Intrathoracic multicentric Castleman disease: CT findings in 12 patients. Radiology 1998;209:477-81.

5.

Casper C. The aetiology and management of Castleman disease at 50 years: translating pathophysiology to patient care. Br J Haematol 2005;129:3-17.

6.

Peterson BA, Frizzera G. Multicentric Castleman's disease. Semin Oncol 1993;20:636-47.

7.

Nishimoto N, Kanakura Y, Aozasa K, Johkoh T, Nakamura M, Nakano S, et al. Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease. Blood 2005;106:2627-32.

8.

Weisenburger DD, Nathwani BN, Winberg CD, Rappaport H. Multicentric angiofollicular lymph node hyperplasia: a clinicopathologic study of 16 cases. Hum Pathol 1985;16:162-72.

9.

Frizzera G, Peterson BA, Bayrd ED, Goldman A. A systemic lymphoproliferative disorder with morphologic features of Castleman's disease: clinical findings and clinicopathologic correlations in 15 patients. J Clin Oncol 1985;3:1202-16.

10.

Iyonaga K, Ichikado K, Muranaka H, Fujii K, Yamaguchi T, Suga M. Multicentric Castleman's disease manifesting in the lung: clinical, radiographic, and pathologic findings and successful treatment with corticosteroid and cyclophosphamide. Intern Med 2003;42:182-6.

11.

Higuchi T, Nakanishi T, Takada K, Matsumoto M, Okada M, Horikoshi H, et al. A case of multicentric Castleman's disease having lung lesion successfully treated with humanized anti-interleukin-6 receptor antibody, tocilizumab. J Korean Med Sci 2010;25:1364-7.

Tuberculosis & Respiratory Diseases

e-Submission OA Policy