A Case of IgG4-Related Lung Disease Presenting as Interstitial Lung Disease
송진우 (서울아산병원)
홍선인 (서울아산병원)
조동휘 (서울아산병원)
채은진 (울산대학교)
송준선 (울산대학교)
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Abstract
Intrathoracic involvement of immunoglobulin G4 (IgG4)-related disease has recently been reported. However, a subset of the disease presenting as interstitial lung disease is rare. Here, we report a case of a 35-year-old man with IgG4-related lung disease with manifestations similar to those of interstitial lung disease. Chest computed tomography showed diffuse ground glass opacities and rapidly progressive pleural and subpleural fibrosis in both upper lobes. Histological findings showed diffuse interstitial lymphoplasmacytic infiltration with an increased number of IgG4-positive plasma cells. Serum levels of IgG and IgG4 were also increased. The patient was diagnosed with IgG4-related lung disease, treated with anti-inflammatory agents, and showed improvement. Lung involvement of IgG4-related disease can present as interstitial lung disease and, therefore, should be differentiated when evaluating interstitial lung disease.
- keywords
- IgG4, Lung Diseases, Lung Diseases, Interstitial
참고문헌
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