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Vol.78 No.4
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Unplanned Extubation in Patients with Mechanical Ventilation: Experience in the Medical Intensive Care Unit of a Single Tertiary Hospital

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2015, v.78 no.4, pp.336-340










& (2015). Unplanned Extubation in Patients with Mechanical Ventilation: Experience in the Medical Intensive Care Unit of a Single Tertiary Hospital. Tuberculosis & Respiratory Diseases, 78(4), 336-340.
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Abstract

Background: Potentially harmful unplanned extubation (UE) may occur in patients on mechanical ventilation (MV)in an intensive care unit (ICU) setting. This study aimed to evaluate the clinical characteristics of UE and its impact onclinical outcomes in patients with MV in a medical ICU (MICU). Methods: We retrospectively evaluated MICU data prospectively collected between December 2011 and May 2014. Results: A total of 468 patients were admitted to the MICU, of whom 450 were on MV. Of the patients on MV, 30 (6.7%)experienced UE; 13 (43.3%) required reintubation after UE, whereas 17 (56.7%) did not require reintubation. Patientswho required reintubation had a significantly longer MV duration and ICU stay than did those not requiring reintubation(19.4±15.1 days vs. 5.9±5.9 days days and 18.1±14.2 days vs. 7.1±6.5 days, respectively; p<0.05). In addition, mortality ratewas significantly higher among patients requiring reintubation than among those not requiring reintubation (54.5% vs. 5.9%; p=0.007). These two groups of patients exhibited no significant differences, within 2 hours after UE, in the fraction ofinspired oxygen, blood pressure, heart rate, respiratory rate, and pH. Conclusion: Although reintubation may not always be required in patients with UE, it is associated with a poor outcomeafter UE.

keywords
Airway Extubation, Respiration, Artificial, Intensive Care Units

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