Severe Endobronchial Inflammation Induced by Aspiration of a Ferrous Sulfate Tablet
손성범 (고려대학교 의과대학 내과학교실)
이정민 (고려대학교 의과대학 내과학교실)
이지애 (고려대학교 의과대학 내과학교실)
정상미 (고려대학교 의과대학 내과학교실)
김정아 (고려대학교 의과대학 내과학교실)
최주환 (고려대학교 의과대학 내과학교실)
김세화 (고려대학교 의과대학 내과학교실)
유아영 (고려대학교 의과대학 내과학교실)
노종아 (고려대학교 의과대학 내과학교실)
박해인 (고려대학교 의과대학 내과학교실)
김원식 (고려대학교 의과대학 내과학교실)
심재겸 (고려대학교 의과대학 내과학교실)
심재정 (고려대학교)
민경훈 (고려대학교 의과대학 내과학교실)
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Abstract
Iron supplements such as ferrous sulfate tablets are usually used to treat iron-deficiency anemia in some elderly patients with primary neurologic disorders or decreased gag reflexes due to stroke, senile dementia, or parkinsonism. While the aspiration of ferrous sulfate is rarely reported, it is a potentially life-threatening condition that can lead to airway necrosis and bronchial stenosis. A detailed history and high suspicion of aspiration are required to avoid delays in diagnosis and treatment. The diagnosis can be confirmed by bronchoscopic examination and a tissue biopsy. Early removal of the aspirated tablet prevents acute complications, such as bronchial necrosis, hemoptysis, and lobar consolidation. Tablet removal is also necessary to prevent late bronchial stenosis. We presented the first case in Korea of a ferrous sulfate tablet aspiration that induced severe endobronchial inflammation.
- keywords
- Foreign Bodies, Respiratory Aspiration, Bronchi, Bronchoscopy
참고문헌
1. Baharloo F, Veyckemans F, Francis C, Biettlot MP, Rodenstein DO. Tracheobronchial foreign bodies: presentation and management in children and adults. Chest 1999;115:1357-62.
2. Lamaze R, Trechot P, Martinet Y. Bronchial necrosis and granuloma induced by the aspiration of a tablet of ferrous sulphate. Eur Respir J 1994;7:1710-1.
3. Boyd M, Watkins F, Singh S, Haponik E, Chatterjee A, Conforti J, et al. Prevalence of flexible bronchoscopic removal of foreign bodies in the advanced elderly. Age Ageing 2009;38:396- 400.
4. Lee JO, Lee JH, Ahn S, Kim JW, Chang H, Kim YJ, et al. Prevalence and risk factors for iron deficiency anemia in the korean population: results of the fifth KoreaNational Health and Nutrition Examination Survey. J Korean Med Sci 2014;29:224-9.
5. Mahmood K, Koubar S, Shofer SL, Ninan NA, Wahidi MM. Alendronate tracheobronchitis. Ann Am Thorac Soc 2013;10: 64-6.
6. Sundar KM, Elliott CG, Thomsen GE. Tetracycline aspiration: case report and review of the literature. Respiration 2001;68: 416-9.
7. Karakan Y, Akpinar A, Yildiz H, Aksoy H, Dikensoy O. A case of ciprofloxacin tablet aspiration. Tuberk Toraks 2010;58:97-9.
8. Micallef J, Montefort S, Mallia Azzopardi C, Galea J. Two cases of aspiration of calcium tablets. Lung India 2011;28:312-4.
9. Radiological notes: aspirated capsule in right lower lobe. J Mt Sinai Hosp N Y 1966;33:530-2.
10. Cimino-Mathews A, Illei PB. Cytologic and histologic findings of iron pill-induced injury of the lower respiratory tract. Diagn Cytopathol 2013;41:901-3.
11. Maw M, Chiu R, Lim AY. Bronchoscopic and histological changes over time following acute ferrous sulphate tablet aspiration. BMJ Case Rep 2012;2012:bcr2012007329.
12. Venci NM, Watson TJ, Kallay MC. Bronchial stenosis following ferrous sulfate aspiration: case report and review of the literature. J Bronchology Interv Pulmonol 2014;21:58-60.
13. Ceylan N, Bayraktaroglu S, Savas R, Alper H. CT findings of high-attenuation pulmonary abnormalities. Insights Imaging 2010;1:287-92.
14. Lee P, Culver DA, Farver C, Mehta AC. Syndrome of iron pill aspiration. Chest 2002;121:1355-7.
15. Kim ST, Kaisar OM, Clarke BE, Vandenburg RA, Allen DH, Bell SC, et al. ‘Iron lung’: distinctive bronchoscopic features of acute iron tablet aspiration. Respirology 2003;8:541-3.
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