- E-ISSN2671-6771
Neonatal Diabetes Mellitus : A Focused Review on Beta Cell Function Abnormalities
Neonatal Diabetes Mellitus : A Focused Review on Beta Cell Function Abnormalities
초록
Neonatal diabetes mellitus, or congenital diabetes mellitus, is a rare genetic disorder caused by abnormal β cell function and other causes. The symptoms of hyperglycemia that occur in neonatal diabetes. The symptoms of hyperglycemia that occur in neonatal diabetes may be transient or persistent. The most frequent genetic cause of neonatal diabetes characterized by abnormal β cell function is abnormalities at the 6q24 locus. Another possible cause is mutations in the ABCC8 or KCNJ11 genes, which code for potassium channels in pancreatic β cells. This underscores the importance of rapid genetic diagnosis following neonatal diabetes diagnosis and highlights the critical timing of sulfonylurea use.
- keywords
- Neonatal Diabetes Mellitus, Gene, 6q24, KAPT channels
Abstract
Neonatal diabetes mellitus, or congenital diabetes mellitus, is a rare genetic disorder caused by abnormal β cell function and other causes. The symptoms of hyperglycemia that occur in neonatal diabetes. The symptoms of hyperglycemia that occur in neonatal diabetes may be transient or persistent. The most frequent genetic cause of neonatal diabetes characterized by abnormal β cell function is abnormalities at the 6q24 locus. Another possible cause is mutations in the ABCC8 or KCNJ11 genes, which code for potassium channels in pancreatic β cells. This underscores the importance of rapid genetic diagnosis following neonatal diabetes diagnosis and highlights the critical timing of sulfonylurea use.
- keywords
- Neonatal Diabetes Mellitus, Gene, 6q24, KAPT channels
- 투고일Submission Date
- 2024-10-15
- 수정일Revised Date
- 2024-10-20
- 게재확정일Accepted Date
- 2024-10-21
- 다운로드 수
- 조회수
- 0KCI 피인용수
- 0WOS 피인용수