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ACOMS+ 및 학술지 리포지터리 설명회

  • 한국과학기술정보연구원(KISTI) 서울분원 대회의실(별관 3층)
  • 2024년 07월 03일(수) 13:30
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ISSN : 0376-4672

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53권 5호

성견의 발치와 협측골 외측에 적용한 교원질 차단막과 재조합골형성단백질의 치조제 보존 효과

Application of rhBMP-2 loaded collagen membrane on the buccal plate for ridge preservation: a pilot study in dogs

임현창 (경희대학교)
김민수 (연세대학교)
양혜주 (연세대학교)
이중석 (연세대학교)
최성호 (연세대학교)
정의원 (연세대학교)
대한치과의사협회지 / The Journal of the Korean Dental Association, (P)0376-4672; (E)2713-7961
2015, v.53 no.5, pp.348-359
https://doi.org/10.22974/jkda.2015.53.5.005
임현창, 김민수, 양혜주, 이중석, 최성호, & 정의원. (2015). 성견의 발치와 협측골 외측에 적용한 교원질 차단막과 재조합골형성단백질의 치조제 보존 효과. 대한치과의사협회지, 53(5), 348-359, https://doi.org/10.22974/jkda.2015.53.5.005

Abstract

Objective: The aim of this study was to determine the effect of multi-layer of a collagen membrane alone or loaded rhBMP-2 on the buccal plate for ridge preservation after tooth extraction. Material and methods: Following bilateral extraction of the maxillary 1st and 3rd premolars in five dogs, rhBMP-2 loaded collagen membrane was applied to the buccal plates at the 1st premolar and collagen membrane only was applied to the buccal plates at the 3rd premolar unilaterally. The collagen membranes applied in the experimental groups were piled into four layers. The corresponding sites of the contralateral side healed naturally. After 3months of healing, the animals were sacrificed. Radiographic and histologic analyses were performed. Results: There was no significant difference in the healing of extraction socket at both 1st and 3rd premolars. In microcomputed tomography, the widths of the residual ridge of the experimental groups were similar with the controls. Histologically, the experimental groups did not exhibit different pattern compared to the controls regardless of the addition of rhBMP-2. Conclusion: Layering of the collagen membrane with or without rhBMP-2 on the buccal plate failed to show the effectiveness in dimensional preservation of the extraction socket.

keywords
collagen membrane, rhBMP-2, ridge preservation, ridge resorption

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