open access
메뉴
open access
메뉴
ISSN : 0376-4672
Purpose : The purpose of this clinical study was to evaluate the effect of chelating and deproteinizing agent containing dental conditioning gel on alleviation of peri-implant mucosa inflammation. Methods: 36 patients with functionally loaded implants for at least 1 year and have clinical signs of peri-implant mucositis were recruited. At baseline, all implants received subgingival prophylaxis with ultrasonic scaler. In the test group, patients were provided a chelating and deproteinizing agent dental conditioning gel (ClinplantⓇ) and were given instructions to applicate it around the implants using an interdental brush for 2 weeks. Chlorhexidine and saline were provided to the positive control group and negative control group, respectively. The modified sulcus bleeding index (mSBI), modified plaque index (mPI), and probing pocket depth (PPD) were evaluated at baseline, 1 week, and 2 weeks. Results: In the ClinplantⓇ and chlorhexidine group, mSBI (-0.81, -0.85 respectively; p<0.01), mPI (-0.46, -0.5 respectively; p<0.01), and PPD (-0.58, -0.48 respectively; p<0.01) at 2 weeks were significantly reduced from baseline. In the saline group, all the clinical parameters were reduced but there was no statistical significance. The saline may be attributed to the influence of prophylaxis at baseline. Conclusions: The present study demonstrated the beneficial clinical effects of chelating and deproteinizing agent containing dental conditioning gel to decrease peri-implant mucosa inflammation equivalent to chlorhexidine. This dental conditioning gel might be useful for alleviation of peri-implant mucosa inflammation.
1. Sanz M, Chapple IL, Working Group 4 of the VEWoP. Clinical research on peri-implant diseases: consensus report of Working Group 4. J Clin Periodontol 2012; 39 Suppl 12:202-6.
2. Roos-Jansaker AM, Lindahl C, Renvert H, Renvert S. Nine- to fourteen-year follow-up of implant treatment. Part II: presence of peri-implant lesions. J Clin Periodontol 2006; 33:290-5.
3. Trejo PM, Bonaventura G, Weng D, Caffesse RG, Bragger U, Lang NP. Effect of mechanical and antiseptic therapy on peri-implant mucositis: an experimental study in monkeys. Clin Oral Implants Res 2006; 17:294-304.
4. Porras R, Anderson GB, Caffesse R, Narendran S, Trejo PM. Clinical response to 2 different therapeutic regimens to treat peri-implant mucositis. J Periodontol 2002; 73:1118-25.
5. Addy M, Prayitno S, Taylor L, Cadogan S. Invitro Study of the Role of Dietary Factors in the Etiology of Tooth Staining Associated with the Use of Chlorhexidine. Journal of Periodontal Research 1979; 14:403-10.
6. Prayitno S, Taylor L, Cadogan S, Addy M. An in vivo study of dietary factors in the aetiology of tooth staining associated with the use of chlorhexidine. J Periodontal Res 1979; 14:411-7.
7. Lee JY, Seol YJ, Park JR, Park YJ, Chung CP. Biological effects of a root conditioning agent for dentin surface modification in vitro. J Periodontal Implant Sci 2010; 40:257-64.
8. Mombelli A, van Oosten MA, Schurch E, Jr., Land NP. The microbiota associated with successful or failing osseointegrated titanium implants. Oral Microbiol Immunol 1987; 2:145-51.
9. Brecx M, Theilade J. Effect of Chlorhexidine Rinses on the Morphology of Early Dental Plaque Formed on Plastic Film. Journal of Clinical Periodontology 1984; 11:553-64.
10. Davies A. The mode of action of chlorhexidine. J Periodontal Res Suppl 1973; 12:68-75.
11. Lang NP, Joss A, Orsanic T, Gusberti FA, Siegrist BE. Bleeding on probing. A predictor for the progression of periodontal disease? J Clin Periodontol 1986; 13:590-6.
12. Luterbacher S, Mayfield L, Bragger U, Lang NP. Diagnostic characteristics of clinical and microbiological tests for monitoring periodontal and peri-implant mucosal tissue conditions during supportive periodontal therapy (SPT). Clin Oral Implants Res 2000; 11:521-9.
13. Yoshida T, Shibata T, Shinohara T, Gomyo S, Sekine I. Clinical evaluation of the efficacy of EDTA solution as an endodontic irrigant. J Endod 1995; 21:592-3.
14. Depamphi.Ml. Dissociation and Reassembly of Escherichia-Coli Outer Membrane and of Lipopolysaccharide, and Their Reassembly onto Flagellar Basal Bodies. Journal of Bacteriology 1971; 105:1184-&.
15. Schnaitman CA. Effect of ethylenediaminetetraacetic acid, Triton X-100, and lysozyme on the morphology and chemical composition of isolate cell walls of Escherichia coli. J Bacteriol 1971; 108:553-63.
16. Hoyos DF, Murray JJ, Shaw L. The effect of chlorhexidine gel on plaque and gingivitis in children. Br Dent J 1977; 142:366-9.
17. Rushton A. Safety of Hibitane. II. Human experience. J Clin Periodontol 1977; 4:73-9.
18. Polson AM, Frederick GT, Ladenheim S, Hanes PJ. The production of a root surface smear layer by instrumentation and its removal by citric acid. J Periodontol 1984; 55:443-6.
19. Pashley DH. Smear layer: physiological considerations. Oper Dent Suppl 1984; 3:13-29.
20. Blomlof J. Root cementum appearance in healthy monkeys and periodontitis-prone patients after different etching modalities. J Clin Periodontol 1996; 23:12-8.