Article Detail

Home > Article Detail
  • P-ISSN 1010-0695
  • E-ISSN 2288-3339

A Study about Quality Control of Herb Medicine Extract Granules – About DanggwiSayeuggaosuyusaenggangtang(DSGOST)

Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2015, v.36 no.4, pp.56-67



Youme Ko (Kyunghee University)











  • Downloaded
  • Viewed

Abstract

Objectives: This study investigated quality among three herb medicine extract granules(DSGOST) which were made from different companies to check quality control of herb medicine extract granules. Methods: we selected three DSGOST extract granules which were made from different companies. And we experimented extract granules by method from K.P(Korean Pharmacopoeia), K.H.P(Korean Herbal Pharmacopoeia) of KFDA. Results: In qualitative analysis of DSGOST, we indentified Akebiae Caulis (木通), Asari Herba Cum Radix (細辛), Evodiae Fructus (吳茱萸) in three different DSGOST extract granules. In quantitative analysis of DSGOST, Medication A,B,C contained similar content of Paeoniflorin & Glycyrrhizic acid. However Medication B contains especially lowest value of Cinnamic acid & total Decursin. Conclusions: Herb medicine extract granules have different contents of ingredients although those were made by same prescription. And these differences may influence medicinal effect to patients. So we need to make system of quality control with various research of quantitative & qualitative analysis about herb medicine extract granules.

keywords
DSGOST(DanggwiSayeuggaosuyusaenggangtang), herb medicine extract granules, quality control


Reference

1

1. Park HM, Choi KH, Jung JY, Lee SD. Metal exposure through consumption of herbal medicine, and estimation of health risk among Korean population. Kor J Env Health. 2006;32:186-91.

2

2. Kim JO, Choi HM, Lee HH, Moon SO, Kim JB, Lee HD. Comparative Study of Characterizing Components and Biological Activities of Bangpungtongseong-san Formulation. Korean J Oriental Physiology & Pathology. 2014;28(3):322-29.

3

3. Baek JH, Kim SM, Ahn JW, Cho CH, Oh MH, Cho JH, Lee MK, Kim HJ. Validation and Determination of Glycyrrhizic Acid as a Marker Substance in Bu-Zhong-Yi-Qi-Tang by HPLC/DAD. J YakhakHoeji. 2008;52(1):7-11.

4

4. Kim HK, Chun JM, Lee AY, Lee HW, Choi JH, Jang S, Ko BS. Quality monitoring of Oriental medicines. Kor J Oriental medicine. 2005;11(2):155-65.

5

5. Lee SD, Kim MD, Park KS. Contamination level and pathway of Herbal Drugs. J oriental preventive medicine. 1998;2(1):209-29.

6

6. Park SJ, Kim SH, Kim KS, Kim HS, Lee AY, Kim HK, Kim YK. A quantitative analysis of marker compounds in single herb extracts by the standard of KHP. Kor J Herbology. 2014;29(3):35-42.

7

7. Zhang ZJ. ‘Jing yue quan shu’ ‘Sanghanron’. Seoul:Daesungmunhwasa. 1993:179.

8

8. Lee YH, Sun SH, Jeong JJ, Park JS, Go HY, Jung KY, Cha YY, Song YK, Kim TH, Hong SI, Choi YK, Ko SK, Lim EM, Park JH, Jeon CY. Literature Review in DanggwiSayeuggaosuyusaenggangtang. Korean J Oriental Physiology & Pathology. 2014;28(1):1-8

9

9. Lee MS, Kim SH, Lim IR. A clinical case study of Tal-juh(脫疽) using DanggwiSayeuggaosuyusaenggangtang. J Institute of Oriental medicine of Daejeon Univ. 1998;7(1):435-43.

10

10. Lee JW. Effects of Danggwisayeokgaosuyuseaggangtang (DSGOS) on the Hypothyroidism of Rats. Graduate school of Daejeon university.

11

11. Kim MK. Danggwisayeokgaohsuyusaenggang-tang on Collagen Induced Arthritis in Mice. Graduate school of Daejeon university.

12

12. Cho YC. Danggwisayeokgaohsuyusaenggang-tang on Adjuvant Induced Arthritis in Rats. Graduate school of Semyung university.

13

13. Pharmaceutical Affairs Law. Korea Ministry of Government Legislation. Retrieved 02.11.2013. from http://www.law.go.kr/main.html.

  • Downloaded
  • Viewed
  • 0KCI Citations
  • 0WOS Citations

Other articles from this issue

Recommanded Articles

상단으로 이동

Journal of Korean Medicine