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  • P-ISSN 1010-0695
  • E-ISSN 2288-3339

한양방결합치료로 장기간 생존하고 있는 교모세포종 증례 보고

Case Report on Long Term Survival of Glioblastoma Patient Treated with Integrative Medicine

대한한의학회지 / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2018, v.39 no.1, pp.75-85
https://doi.org/10.13048/jkm.18008
양주노 (경희예당한의원)
윤영주 (부산대학교)
홍진우 (부산대학교)
한창우 (부산대학교)
권정남 (부산대학교)
이인 (부산대학교)
박성하 (부산대학교)
김소연 (부산대학교)
최준용 (부산대학교)
이혜윤 (부산대학교 한의학전문대학원 한의학과)
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Abstract

Objectives: This is a long-term survival case report about glioblastoma treated with western medicine and traditional Korean medicine. 28 year-old man diagnosed glioblastoma in 2003 went through 2 year's chemotherapy first. After emergency brain surgery he took acupuncture and Korean herbal medication including Dohongsamul-tang and Boan-Manyeongdan in addition to conventional radiotherapy and chemotherapy for 3 years. Since May 2008, he was exclusively treated with traditional Korean medicine except taking antiplatelets only for 9 years. Though he hassequelae of tumor necrosis such as facial palsy and hemiparesis, he has survived without recurrence more than 14years. We suggest that integrative approach including traditional Korean medicine can be a meaningful treatment option for malignant brain tumor. Further studies with more cases should be performed to establish proper treatment protocol of integrative medicine for brain tumor.

keywords
Glioblastoma, Traditional Korean Medicine, Integrative Medicine


참고문헌

1

Louis DN, Perry A, Reifenberger G, Deimling A, Figarella-Branger D, Cavenee WK, et al. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathol. 2016; DOI 10.1007/s00401-016-1545-1.

2

Nicholas S, Mathios D, Ruzevick J, Jackson C, Yang I, Lim M. Current Trends in Glioblastoma Multiforme Treatment: Radiation Therapy and Immune Checkpoint Inhibitors. Brain Tumor Res Treat. 2013;1:2-8.

3

Jung KW, Yoo H, Kong HJ, Won YJ, Park S, Lee SH. Population-based survival data for brain tumors in Korea. J neurooncol. 2012;109:301-307.

4

Jeong JS, Park JW, Yoon SW. A Case of Metastatic Brain Tumor Patient with Nausea and Vomiting Treated with Gamibokryungbanha-tang. Korean J Orient Int Med. 2007;28(4):956-962.

5

Jeong UM, Kim HM, Jeong JS, Lee JS, Kim KS, Yoon SW. A Case Report of Regressed Metastatic Brain Tumors and Prolongation of Life with Allergen Removed Rhus verniciflua Stokes after Gamma Knife Radiosurgery. J Korean Med. 2009;30(5):157-162.

6

Kang Th, Won JH. Clinical Study on 1 Case of Patient with Astrocytoma. J Korea Oriental Oncology. 2000;6(1):181-188.

7

Wang Z, Chen S, Wang L. A Comprehensive Curative Effect of Malignant Brain Tumors Treated With VM26+MeCCNU and TCM. Cancer Prev Treat Res. 2000;27(2):152-153.

8

Zhou J, Liu H, Zhao M. Clinical research on Naoliu (Brain Tumor) powder in treating brain gliomas. Tianjin J Trad Chinese Med. 2008;25(4):277-280.

9

Fan Y, Hu Y, Li Y. Antifebrile Effect of Naoreqing oral Liquid on Post-operational Fever of Glioma or Meningioma Patients. Cninese J Int Med. 2001;21(6):406-408.

10

Zhang J. Analysis of Application of High Doses of Aconite Treatment of Typical Cases of Brain Tumor. Systems Med. 2016;1(4):60-63.

11

Sun W, Cui J, Zhu Y, Cao Y, Sun Y, Wang Z. Discussion and Analysis of Contemporary Famous Chinese Medicine Experts' Clinical ExPeriences in Treating Brain Tumors. J Liaoning Univ TCM. 2014;16(4):59-60.

12

Guo C, Zhu G. Summary of the Features of Qian Bowen's Thoughts on Clinical Treatment of Brain tumor. World Chinese Med. 2015;10(10):1552-1554.

13

Dolecek TA, Propp JM, Stroup NE, Kruchko C. CBTRUS statistical report:primary brain and central nervous tumors diagnosed in the United States in 2005-2009. Neuro Oncol. 2012;14(suppl5):v1-v49.

14

Do YS, Jung KW, Ha J, Seo Y, Park CK, Won YJ. et al. An Updated Nationwide Epidemiology of Primary Brain Tumors in Republic of Korea, 2013. Brain Tumor Res Treat. 2017;5(1):16-23.

15

Omuro A, DeAngelis LM. Glioblastoma and Other Malignant Gliomas : A Clinical Review. JAMA. 2013;310(17):1842-1850.

16

Chung M J, Park JY, Bang S, Park SW, Chung JB, Song SY. Phase II clinical trial to evaluate the efficacy and safety of activated T-lymphocyte cell therapy in gemcitabine refractory advanced pancreatic cancer. Pancreatology. 2013;13(4), S45.

17

Shin YS, Lee JA, Bae SH, Lee SY, Jang MK. Investigation into the Use of Complementary and Alternative Medicine and Factors Affecting Use in Korean Patients with Brain Tumors. J Korean Acad Fundam Nurs. 2013;20(2):147-156.

18

Lee JK, Song YK, Lim HH. Analgesic and anti-inflammatory effect of Scutellaria baicalensis. J Korean Med. 2007;28(4):124-135.

19

Lee HY, Kim JE, Kim M, Kim JH. A review of traditional Korean medical treatment for cancer-related cognitive impairment. J Korean Med. 2016;37(3):74-86.

20

Verlut C, Mouillet G, Magnin E, Buffet-Miny J, Viennet G, Cattin F, et al. Age, Neurological Status MRC scale, and Postoperative Morbidity are Prognostic Factors in Patients with Glioblastoma Treated by Chemoradiotherapy. Clinical Med Insight: Oncology. 2016:1077-1082.

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