- P-ISSN 1010-0695
- E-ISSN 2288-3339
- Apply for Authority
- P-ISSN1010-0695
- E-ISSN2288-3339
Article Detail
Home > Article Detail
Anti-hypertensive effect by Single adminstration of Chunghyul-dan : A CASE SERIES
Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2018, v.39 no.1, pp.95-103
https://doi.org/10.13048/jkm.18010
&
(2018). Anti-hypertensive effect by Single adminstration of Chunghyul-dan : A CASE SERIES. Journal of Korean Medicine, 39(1), 95-103, https://doi.org/10.13048/jkm.18010
- Downloaded
- Viewed
Abstract
Objectives: This study was designed to investigate antihypertensive effect by single adminstration of Chunghyul-dan in stroke patients. Methods: This is a 31-patient case series from retrospective chart review of inpatients who diagnosed with stroke at a Kyung Hee University Korean Medicine Hospital (Seoul) between October 2016 to October 2017. We reviewed patient’s charts with transient and sudden increases in blood pressure who were treated with Chunghyul-dan and analyzed blood pressure over time. In addition we classified patients by using the standardized predictive models for Korean medical diagnostic pattern-identification to find out if there are some differences in responder ratios. Results: Thirty one patients who took Chunghyul-dan were identified. 60 minutes, 120 minutes after 1200mg administration, systolic and diastolic blood pressure decreased significantly compared to baseline. We could not identify the difference between the groups of each pattern-identification because of small number of some groups. Conclusions: Although limited by its retrospective nature, this study suggests that Chunghyul-dan may be effective as short term antihypertensive method for stroke patient.
- keywords
- Chunghyul-dan, Hypertension, Stroke, Diagnostic Pattern identification, Antihypertensive effect
Reference
1
Chung KH, Choi YS, Kim LD, Kim JR, Jung WS, Moon SK, et al. Effects of chunghyul-dan on serum lipids in patients with hyperlipidemia. Korean Journal of Oriental Internal Medicine. 2003;24(3):543-550.
2
Yun SP, Jung WS, Park SU, Moon SK, Ko CN, Cho KH, et al. Anti-hypertensive Effect of Chunghyul-dan on Stroke patients with essential hypertension. The American Journal of chinese Medicine. 2005;33(3):357-364.
3
Park SU, Jung WS, Moon SK, Ko CN, Cho KH, Kim YS, et al. Chunghyul-Dan (Qingxie-dan) improves arterial stiffness in patients with increased baPWV. The American Journal of Chinese Medicine. 2006;34(4):553-563.
4
Park SU, Jung WS, Moon SK, Ko CN, Cho KH, Kim YS, et al. Chunghyul-dan activates NOS mRNA expression and suppresses VCAM-1 mRNA expression in human endothelial cells. Canadian Journal of Physiology and Pharmacology. 2005;83(12):1101-1108.
5
Ko CN, Park IS, Park SU, Jung WS, Moon SK, Park JM, et al. Neuroprotective effect of Chunghyul-dan (Qing Xue Dan) on hypoxia-reoxygenation induced damage of neuroblastoma 2a cell lines. Chinese Journal of Integrative Medicine. 2013;19(12):940-944.
6
Jung WS, Kwon SW, Cho SY, Park SU, Moon SK, Park JM, et al. The effects of Chunghyul -dan(a korean medicine herbal complex) on cardiovascular and cerebrovascular diseases : A narrative review. Evidence-Based Complementary and Alternative Medicine Volume. 2016;2016:1-10.
7
Yun SP, Kim LD, Lee SH, Kim EJ, Park YM, Jung WS, et al. Effects of Chunghyul-dan (Qingxue-dan) on stroke patients with stage 1 hypertension -Preliminary study for optimal dose- . The Journal of Internal Korean Medicine. 2004;2004:74-81.
8
Collins R, Peto R, MacMahon S, Hebert P, Fiebach NH, Eberlein KA, et al. Blood pressure, stroke, and coronary heart disease. Part 2: short term reductions in blood pressure : overview of randomized drug trials in their epidemiological context. Lancet. 1990;335:827-838.
9
Kim CH, Kim YS, Park YK. Management of Hypertension in Primary Care. Korean J Fam Pract. 2012;2:8-14.
10
Shin MS, Han CH, Kim BY, Kim KJ, Park SH, Choi SM. A study on the recognition and actual condition of Korea medical doctors in oriental medical care of hypertension. The journal of Korean Acupuncture & Moxibustion Society. 2008;25(6):23-33.
11
Kwon SW. Development of standardized predictive models for Korean Medical Diagnostic Pattern-identification in stroke subjects. Seoul: Kyunghee Univ; 2016.
12
Law MR, Wald NJ, Morris JK, Jordan RE. Value of low dose combination treatment with blood pressure lowering drugs: analysis of 354 randomized trials. BMJ. 2003;326:1-8.
13
Ettehad D, Emdin CA, Kiran A, Anderson SG, Callender T, Emberson J, et al. Blood pressure lowering for prevention of cardiovascular disease and death: A systematic review and meta-analysis. Lancet. 2016;387:957-967.
14
Kopunek SP, Michael KM, Shaughnessy M, Resnick B, Nahm ES, Andrew Goldberg JW, et al. Cardiovascular Risk in Survivors of Stroke. American journal of preventive medicine. 2007;32(5):408-412.
15
Wang Tao. Wai Tai Mi Yao Fang. First edition. Taipei:Taiwan shang wu yin shu guan. 1983:542
16
Kook YB. Effect of Hwangryunhaedok-tang on blood pressure and renal functions in spontaneously hypertensive rats. The Korean Journal of Oriental Medical Prescription. 2002;10(1):113-129.
17
Kim YS, Jung EA, Shin JE, Chang JC, Yang HK, Kim NJ, et al. Daio-Orengedokuto inhibits HMG-CoA reductase and pancreatic lipase. Biological and Pharmaceutical Bulletin. 2002;25:1442-1445.
18
Sanae F, Komatsu Y, Amagaya S, Chisaki K, Hayashi H. Effects of 9 Kampo medicines clinically used in hypertension on hemodynamic changes induced by theophylline in rats. Biological and Pharmaceutical Bulletin. 2000;23(6):762-765.
19
Sanae F, Komatsu Y, Chisaki K, Kido T, Ishige A, Hayashi H. Effects of San'o-shashin-to and the constituent herbal medicines on theophylline-induced increase in arterial blood pressure of rats. Biological and Pharmaceutical Bulletin. 2001;24(10):1137-1141.
20
Hwang DS, Kim HG, Kim TM, Lee TH, Oh MS. The Effect of Hwangryunhaedok-tang on the c-fos Level in mice exposed to heat stress. J Korean Obstet Gynecol. 2014;27(3):1-11.
21
Kim HJ, Bae HS, Park SU, Moon SK, Park JM, Jung WS. Clinical approach to the standardization of oriental medical diagnostic pattern identification in stroke patients. Evid Based Complement Alternat Med. 2011;2011:1-7.
- Downloaded
- Viewed
- 0KCI Citations
- 0WOS Citations
Other articles from this issue
- Effects of Topical application of Astragalus membranaceus in Spontaneous Alopecia Mice Model
- Comparison of Health Status and Mibyeong Characteristics between Cold Syndrome and Heat Syndrome by Cold Heat Syndrome Differentiation Score
- Comparative study on the contents of marker compounds and anti-inflammatory effects of Gamisoyo-san decoction according to storage temperature and periods
- Protective effect of furosin isolated from Euphorbia helioscopia against glutamate-induced HT22 cell death
- The Effect of Drinking Alcohol on Bio-electrical Potential at Twelve Source Points : A Cross-over Study
- Study on the Nomenclature of Acupoints for the Healthcare Terminology Standard.
- The effects of Eclipta Prostrata L.(Ecliptae Herba) on periodontitis rats
- Case Report on Long Term Survival of Glioblastoma Patient Treated with Integrative Medicine
- The Effect of Geopungchunghyul-dan on Circumferential Strain of Carotid Artery: A Case Series
- Anti-hypertensive effect by Single adminstration of Chunghyul-dan : A CASE SERIES
- more
Recommanded Articles
This website recommended the use the Chrome browser for journal website.