- 권한신청
- E-ISSN2586-7342
- KCI
HIV/AIDS Management: Dolutegravir Based Antiretroviral Drug Therapy
Emmanuel, Okoh Emeka (1Brigade Medical centre)
Anthonia, Ikpeama Chizoba (Nursing Department Usmanudanfodiouniversity teaching Hospital Sokoto)
Joy, Ikpeama Chinwe (Medicine San Frontires)
Adimabua, Okafor Patrick (School of Medical Laboratory Sciences Ahmadu Bello University)
Osazuwa, Igbineweka Osa (Department of Periodontology And Community Dentistry, University College Hospital)
Andrew, Ikpeama Emeka (Anatomy Department Anambra State University Uli)
Mariam, Onuzulike Nonye (Department of Public Health Imo State University)
Gami, Hilary Tumba (1Brigade Medical centre)
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Abstract
HIV/AIDS disease still remain a global pandemic and it's management has undergone series of treatment changes and improvement although there is still no permanent cure.Dolutegravir belongs to a group of HIV drugs called integrase inhibitors. Integrase inhibitors block an HIV enzyme called integrase. By blocking integrase, integrase inhibitors prevent HIV from multiplying and can reduce the amount of HIV in the body.Dolutegravir combination based regimen has turned out to be very effective (antiviral) with negligible rare side effects on clients. This drug (Dolutegravir based regimen) combination has successfully increased the appetite for food of all the clients, unlike others and has shown to reduce viral load in the most shortest period ever. It can be deduced that development of resistant mutant virus will be reduced if not eliminated with dolutogravir based regimen.The role of Continuous adherence counseling has shown to improve clients treatment management. It is important to note that the availability of food has direct effect on the economic status or financial weight on the client. Hence the progress that is increase in body mass index (BMI) is a direct impact of the availability of food for the clients.
- keywords
- HIV/AIDS, Dolutegravir, Adherence counseling, Treatment
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