This study is a descriptive survey research to identify factors affecting the nursing intention of nursing college students who will nurse COVID-19 patients. This study was analyzed through convenience sampling for freshmen, sophomore, junior, senior attending the Department of Nursing at E University in Gyeonggi-do from May 17 to August 11, 2022. As a result, it was found that the intention to care for COVID-19 patients increased by 20% every time the knowledge score on COVID-19 increased by 1 point . If the average score for each item in the moral sensitivity question increased by 1 point, the nursing intention increased significantly by 5.21 times, and it was found that the nursing intention for COVID-19 patients increased significantly by 6.93 times each time the average score for each behavioral belief item increased by 1 point. Based on the results of this study, it was confirmed that the higher the knowledge, moral sensitivity, and behavioral beliefs of nursing students, the higher the intention to care for new infectious disease patients. Based on the results of this study, it was confirmed that It is necessary to develop and apply educational and psychological intervention programs and integrated nursing ethics programs.