Background: "Leave blank" is a unique expression technique in Chinese painting. It has the unique charm of Chinese national culture. This article analyzes the artistic "Blank Space" expression in freehand brushwork flower and bird paintings from an aesthetic perspective. In aesthetics field, artistic beauty is an essential category. It can also be seen as a study of the aesthetic relationship between humans and the objective world. The "Blank Space" in Chinese freehand flower and bird paintings is important in ancient Chinese art. Purpose: The word "Blank Space" is easily understood and is a commonly used expression technique in Chinese art. It has strong Chinese aesthetic characteristics. This article analyzes the connotation and significance of "Blank Space". It studies freehand brushwork, composition, expression, and formal beauty of “Blank Space”. It elaborates the aesthetic expression of “Blank Space” in freehand flower and bird paintings. Furthermore, it has created various artistic beauty that make people feel graceful, melodious, and melancholic, with endless aftertaste. Methods: Based on the literature, analyze the art of leaving white space in the painting from an aesthetic perspective. Understand and master the importance of leaving white space in freehand flower and bird paintings comprehensively and correctly. Results: The application of "Blank Space" in the painting reflects the aesthetic taste of Chinese painting. It is the unique charm of traditional Chinese art. The "Blank Space" artistic techniques enriches and develops the artistic style of Chinese freehand flower and bird painting. Conclusion: The artistic conception, implicit beauty, spatial sense, and rhythmic rhythm of the screen perfectly express the "blank" art of Chinese freehand brushwork of flowers and birds. Blank space art uses "Blank Space" as a carrier to render beautiful artistic conceptions with strong Chinese aesthetic characteristics. Most works combine virtual and real, bringing readers a higher aesthetic enjoyment. It expands the hierarchical layout of the space, leaving room for imagination.