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Tuberculosis & Respiratory Diseases

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Vol.61 No.3
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만성활동성C형간염에 대한 인터페론 치료 후 사르코이드증의 악화

Exacerbation of Sarcoidosis Following Interferon-alpha Therapy for Chronic Active Hepatitis C

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2006, v.61 no.3, pp.285-288
장혜정
이진화 (이화여자대학교)
김태헌 (이화여자대학교)
문진욱 (연세대학교)
김유경 (이화여자대학교)
천은미 (이화여자대학교)
성순희 (이화여자대학교)
장중현 (이화여자대학교)
최은화 (이화의대)
김인제 (이화의대)
심윤수 (이화의대)
장혜정, 이진화, 김태헌, 문진욱, 김유경, 천은미, 성순희, 장중현, 최은화, 김인제, & 심윤수. (2006). 만성활동성C형간염에 대한 인터페론 치료 후 사르코이드증의 악화. Tuberculosis & Respiratory Diseases, 61(3), 285-288.
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초록

인터페론 알파는 만성활동성C형간염 환자에서 항바이러스제로 사용되는 면역조절제로, 인터페론 치료가 사르코이드증을 발생시키거나 악화시킬 수 있다고 알려져 있다. 저자 등은 C형간염바이러스 활성화로 인터페론과 ribavirin으로 치료를 받은 후 기존의 폐사르코이드증이 악화되었다가 자연 호전된 예를 경험하였기에 보고하는 바이다.

keywords
Hepatitis C, Interferon, Sarcoidosis., Hepatitis C, Interferon, Sarcoidosis.

Abstract

Interferon alpha is an immunomodulator that is used as an antiviral agent to treat chronic active viral hepatitis C. However, interferon can induce or exacerbate sarcoidosis. We report a case of 42-year-old man with an exacerbation of pulmonary sarcoidosis after the cessation of interferon and ribavirin therapy for chronic hepatitis C. The patient's sarcoidosis improved spontaneously and he continues to be monitored regularly without steroid therapy. (Tuberc Respir Dis 2006; 61: 285-288)

keywords
Hepatitis C, Interferon, Sarcoidosis., Hepatitis C, Interferon, Sarcoidosis.

참고문헌

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Tuberculosis & Respiratory Diseases

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