폐모세포종은 폐종양으로 매우 드물게 나타나며 드물게 간, 흉외 림프절, 심장으로 전이된다고 보고되고 있다. 본 저자들은 복부의 팽만감과 통증 및 호흡곤란을 주소로 내원한 환자에서 간과 폐의 거대 종괴를 발견하였고, 조직 검사를 통하여 간, 횡격막, 심장 등 다발성 침범을 동반한 폐모세포종으로 진단받은 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.
A pulmonary blastoma is a rare malignant tumor of the lung that is composed of epithelial and mesenchymal elements and resembles the structure of an embryonic lung. Pulmonary blastomas have a very poor prognosis and make up 0.25 to 0.5 percent of all primary malignant lung tumors. A pulmonary blastoma usually manifests as a solitary parenchymal mass or nodule and multiple subpleural mass with effusion on chest X-ray and computed tomography. We encountered a very rare case of pulmonary blastoma in a 52 years old male. He complained of abdominal pain, fullness, and dyspnea. The radiology examination revealed a huge lung mass invading the mediastinum, heart, diaphragm, and liver. The percutaneous needle biopsies were performed, and this tumor was diagnosed as a pulmonary blastoma. We report a biopsy confirmed case of a huge pulmonary blastoma invading multiple organs. (Tuberc Respir Dis 2007; 62: 149-153)
(2006) Survival of biphasic pulmonary blastoma,
(1996) Pulmonary blastoma: a rare lung malignancy,
(1997) Pulmonary blastoma in adults,
(actapatholmicrobiolscand1980;88) aclinico- pathological study of eleven cases,
(1995) Resection and adjuvant chemotherapy of pulmonary blastoma: a case report,
(2004) Small cell carcinoma, and sarcomatoid carcinoma. In: World Health Organization Classification of Tumours. Pathology and genetics of tumours of the lung, pleura, thymus and heart, Lyon: IARC Press 2004
immunohistochemical investigations of three cases, Dienemann D Minck C
(2006) Pulmonary blastoma: a rare tumor with variable presentation,
(2001) Extension of a pulmonary blastoma into the left atrium,
Lee HJ, (2004) Pulmonary blastoma:radiologic findings in five patients,
Robert J, (2002) Pulmonary blastoma: report of five cases and identification of clinical features suggestive of the disease,