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Tuberculosis & Respiratory Diseases

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Vol.76 No.4
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A Case of IgG4-Related Disease Presenting as Massive Pleural Effusion and Thrombophlebitis

Tuberculosis & Respiratory Diseases / Tuberculosis & Respiratory Diseases,
2014, v.76 no.4, pp.179-183














& (2014). A Case of IgG4-Related Disease Presenting as Massive Pleural Effusion and Thrombophlebitis. Tuberculosis & Respiratory Diseases, 76(4), 179-183.
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Abstract

Immunoglobulin (Ig) G4-related disease is a recently recognized systemic fibroinflammatory condition characterized by a lymphoplasmacytic infiltrate rich in IgG4-positive plasma cells with elevated circulating levels of IgG4. The disease can either be localized to one or two organs, or present as diffuse multi-organ disease. Furthermore, lesions in different organs can present simultaneously or metachronously. In the pulmonary manefestations, lesions associated with IgG4-related disease have been described in the lung parenchyma, airways and pleura, as well as the mediastinum. We report a case of IgG4-related disease presenting as massive pleural effusion and thrombophlebitis.

keywords
Immunoglobulin G, Pleural Effusion, Thrombophlebitis

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