바로가기메뉴

본문 바로가기 주메뉴 바로가기

ACOMS+ 및 학술지 리포지터리 설명회

  • 한국과학기술정보연구원(KISTI) 서울분원 대회의실(별관 3층)
  • 2024년 07월 03일(수) 13:30
 

logo

메뉴

권호 목록

정상 상악동의 영상소견
이완(원광대학교) pp.472-478 https://doi.org/10.22974/jkda.2008.46.8.001
상악동 내인성 질환의 영상진단
김진수(조선대학교 치과대학) pp.479-485 https://doi.org/10.22974/jkda.2008.46.8.002
상악동 외인성 질환의 영상진단
한진우(강릉대학교 치과대학) pp.486-493 https://doi.org/10.22974/jkda.2008.46.8.003
타이타늄 임플란트 골유착시 성장인자들의 발현 ;TGF-β, IGF-I, BMP2, BMP4
지유진(경희대학교 동서신의학병원) ; 김수현(경희대학교 동서신의학병원) pp.494-504 https://doi.org/10.22974/jkda.2008.46.8.004
초록보기
초록

Abstract

Osseointegration is a result of bone formation and bone regeneration process, which take place at the interface between bone and implant and biologic determinants such as cytokine, growth factors, bone matrix proteins play an important role in osseointegration. The purpose of this study is to compare the expression of TGF-β, IGF-I, BMP2, BMP4 during osseointegration. We designed an experimental group which was inserted with a RBM surface titanium implants and machined surface, and compared with a control group which had a simple bone cavity and normal bone. Titanium implants were placed into tibia of 8 rabbits. We compared the expression of TGF-β, IGF-I, BMP2, BMP4 using RT-PCR (reverse transcriptase chain reaction) analysis in day 3, 7, 14 and 28 of implant insertion. According to the results, growth factors of experimental groups were more expressed than control groups. Among experimental groups, expression of TGF-β, IGF-I, BMP-4 of RBM group had tendency to increase more at 14th, 28th days than Machined surface group. Therefore, our results suggest that TGF-β, IGF-I, BMP4 are expressed within the bone around the implant and more increased around rough surface implants while osseointegration occurs after dental implant insertion.

logo