ACOMS+ 및 학술지 리포지터리 설명회

  • 한국과학기술정보연구원(KISTI) 서울분원 대회의실(별관 3층)
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  • P-ISSN 1010-0695
  • E-ISSN 2288-3339

난소절제 흰쥐의 골대사에 미치는 鼈甲의 영향

Effects of Amydae Carapax on Bone Metabolism in Ovariectomized Rats

대한한의학회지 / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2002, v.23 no.3, pp.472-480
박종혁 (혜당한방병원)
윤철호 (동국대학교)
정지천 (동국대학교)
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Abstract

Objectives : This study was undertaken to investigate the effects of Amydae Carapax (AC) on parameter related to bone metabolism in ovariectomized rats.Methods : We measured alkaline phosphatase activity and contents of estrogen, calcium, hydroxyproline, osteocalcin, calcitonin and parathyroid hormone after the ovariectomized rats were treated with AC for 30 days.Results : Serum estrogen, calcium and calcitonin contents in ovariectomized rats were significantly decreased, but by AC treatment were increased. Significant increasement of serum alkaline phosphatase activity, parathyroid hormone activity and osteocalcin content in ovariectomized rats was remarkably decreased by AC treatment. Increasement of urinary calcium and hydroxyproline contents in ovariectomized rats was decreased by AC treatment.Conclusions : These results shows that AC have ability which recover abnormal calcium metabolic process by sex hormone inequality, promoting bone absorption and inhibiting bone formation.

keywords
Amydae Carapax, estrogen, calcium, ovariectomy, osteoporosis, Amydae Carapax, estrogen, calcium, ovariectomy, osteoporosis


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