- P-ISSN 1010-0695
- E-ISSN 2288-3339
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- P-ISSN1010-0695
- E-ISSN2288-3339
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Effects of Amydae Carapax on Bone Metabolism in Ovariectomized Rats
Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2002, v.23 no.3, pp.472-480
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(2002). Effects of Amydae Carapax on Bone Metabolism in Ovariectomized Rats. Journal of Korean Medicine, 23(3), 472-480.
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Abstract
Objectives : This study was undertaken to investigate the effects of Amydae Carapax (AC) on parameter related to bone metabolism in ovariectomized rats.Methods : We measured alkaline phosphatase activity and contents of estrogen, calcium, hydroxyproline, osteocalcin, calcitonin and parathyroid hormone after the ovariectomized rats were treated with AC for 30 days.Results : Serum estrogen, calcium and calcitonin contents in ovariectomized rats were significantly decreased, but by AC treatment were increased. Significant increasement of serum alkaline phosphatase activity, parathyroid hormone activity and osteocalcin content in ovariectomized rats was remarkably decreased by AC treatment. Increasement of urinary calcium and hydroxyproline contents in ovariectomized rats was decreased by AC treatment.Conclusions : These results shows that AC have ability which recover abnormal calcium metabolic process by sex hormone inequality, promoting bone absorption and inhibiting bone formation.
- keywords
- Amydae Carapax, estrogen, calcium, ovariectomy, osteoporosis, Amydae Carapax, estrogen, calcium, ovariectomy, osteoporosis
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