- P-ISSN 1010-0695
- E-ISSN 2288-3339
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- P-ISSN1010-0695
- E-ISSN2288-3339
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The Experimental study of Jungchun-tang on Allergies
Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2003, v.24 no.3, pp.495-501
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(2003). The Experimental study of Jungchun-tang on Allergies. Journal of Korean Medicine, 24(3), 495-501.
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Abstract
This report describes an inhibitory effect of Jungchuntang(JCT) on immediate hypersensitivity through IgE/mast cell/mediator pathaway. JCT is an Oriental herbal medication, which has been used for the treatment of allergic patients with espatially asthma in Korea. JCT significantly inhibited the IgE production in mice and IL-4 + anti CD40-mediated IgE production in vitro. JCT promoted IFN-expression but inhibited IL-4 and IL-6 mRNA expression. JCT dose-dependently inhibited the compound 48/80-induced histamine release from mast cell line, IC-2 cell. Thease results indicated that JCT has treatmentary effect on atopic disorder, such as asthma.
- keywords
- Jungchuntang, IL-4, IL-6, anti CD40, IgE Production, Histamine, Jungchuntang, IL-4, IL-6, anti CD40, IgE Production, Histamine
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