- P-ISSN 1010-0695
- E-ISSN 2288-3339
- Apply for Authority
- P-ISSN1010-0695
- E-ISSN2288-3339
Article Detail
Home > Article Detail
Effect of Chungsimyeonjaeum on myocardiac cell injury in mouse myoblast C2C12 cells
Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2006, v.27 no.3, pp.25-36
&
(2006). Effect of Chungsimyeonjaeum on myocardiac cell injury in mouse myoblast C2C12 cells. Journal of Korean Medicine, 27(3), 25-36.
- Downloaded
- Viewed
Abstract
Determination and differentiation of cells in the skeletal muscle lineage is positively regulated by cell-cell contact. Differentiation proteins proposed to mediate this effect include both classical MyoD and MEF members; potential interactions between the promyogenic activities of these classes of protein, however, are unknown. We show here that MyoD and MEF, two promyogenic family members that determine to each other in a cis fashion, form ineraction with MyoD and MEF. These proteins contain myosin heavy chain and are enriched at sites of cell-cell contact between myoblasts. Therefore, in differentiation of MyoD MEF from Chungsimyeonjaeum interact dependently, suggesting that the interactions occur in a cis fashion; consistent with this conclusion, MyoD-mediated differentiation is required for myoblast to occur by Chungsimyeonjaeum. Inhibition in myoblasts of a MyoD by Staurosporine in its ability to associate with MEF interferes with differentiation as assessed by morphological and transcription level, suggesting that this interaction is functionally important in myogenesis. Also, some of the differentiation-mediated proteins that are required for myogenesis seem to be based on interdependent activities of promyogenic classical smad-subfamilly.
- keywords
- MyoD, MEF, Chungsimyeonjaeum
- Downloaded
- Viewed
- 0KCI Citations
- 0WOS Citations
Other articles from this issue
- Effect of Crude Saponin of Korea Red Ginsengon High Fat Diet-induced Obese Rats
- Effects of Samjunghwan on Obesity and Lipid Metabolism in High Fat Diet Rats
- Effect of Chungsimyeonjaeum on myocardiac cell injury in mouse myoblast C2C12 cells
- Effects of Korean ginseng, Korean red ginseng and Fermented Korean red ginseng on Cerebralblood flow, Cerebrovascular reactivity, Systemic blood pressure and Pulse rate in Humans
- The Effects of Phellodendri Cortex Treatment on Hematological and Cyto-pathological Alterations in Non-Bacterial Prostatitis Rat Model
- Administration Duration Dependent Effects of Morindae Radix Extract Solution on the Reproductive Capacities in the Mice
- Beneficial Effect of Samgijiwhang-Tang on Diabetic Nephropathy Rats
- Immunological Study of the Gami-sopunghwalhyeol tang(Ji？w？i-sh？f？nghu？xu？-tang: GSHT) on Rheumatoid Arthritis in Human Fibroblast-like Synoviocytes
- The Effect of Dansamtongmek-tang and Dansamsengmek-san on Hyperlipidemia and Brain & Cell Damage by Hypoxia
- The Study About Features Of The Primitive Meridian System.
- A Study on Repducibility of responses to the Questionnaire of Sasang Constitiution Classification Ⅱ(QSCCⅡ)
- Research Trends in Complementary Medical Therapy for Common Cold
- The Effects of Dioscorea bulbifera L. on the Hyperthyroidism of Rats
- The Effects of Radix Scrophulariae(玄蔘) on the Hyperthyroidism of Rats
- Effect of GB 34-GB 39 Electro-acupuncture on Regional Cerebral Blood Flow in Stroke Patients and Normal Volunteers Evaluated by 99mTc-ECD SPECT
- Objective Evaluation of Sublingual Veins Using Color Differences
- The Study of Literature on Meridians and Acupoints about Acupncture Treatment of Alopecia.
- Perspective on the development of the cooperation group standardsof acupuncture needles for single use in Korea
- A Clinical Study for Recurrence Rate of Chronic Paranasal Sinusitis in Adults
- Relationship between blood stasis and arterial stiffness in the patientwith ischemic stroke
- more
Recommanded Articles
This website recommended the use the Chrome browser for journal website.