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  • P-ISSN 1010-0695
  • E-ISSN 2288-3339

Relationship between blood stasis and arterial stiffness in the patientwith ischemic stroke

Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2006, v.27 no.3, pp.250-260














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Abstract

Backgrounds : Blood stasis is known as an important pathologic factor for vascular disorder in Oriental medicine. Despite of its clinical importance there has been few objective test for diagnosing blood stasis. Objectives : This study was designed to examine the relationship between blood stasis and arterial stiffness measured by cardio-ankle vascular index(CAVI). Methods : The subjects were 104 ischemic stroke patients with onset after 14 days. Their general characteristics, lipid profiles and uric acid were recorded. The degree of arterial stiffness was assessed by CAVI, and blood stasis was evaluated by diagnostic criteria. The data were analyzed by chi-square test, student t-test, spearman correlation analysis, and pearson correlation analysis. And then, stepwise multiple logistic regression analysis was applied in order to exclude the interactions among several factors. Results : There were significant differences in right, left and higher CAVI between blood stasis group and non blood stasis group(p-value<0.01). Age, systolic blood pressure, triglyceride and CAVI had relationships with blood static score. In multiple logistic regression analysis, the adjusted odds ratio of blood stasis for arterial stiffness with CAVI above 9 were 7.091(95% confidence interval, 1.641~30.638). Conclusions : The results demonstrated the relationship between blood stasis and arterial stiffness measured by CAVI. Therefore, we suggest that CAVI should be one of the objective tests for diagnosing blood stasis.

keywords
blood stasis, cardio-ankle vascular index(CAVI), arterial stiffness


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