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  • P-ISSN 1010-0695
  • E-ISSN 2288-3339

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뇌경색환자의 어혈변증과 동맥경직도의 관련성 연구

Relationship between blood stasis and arterial stiffness in the patientwith ischemic stroke

대한한의학회지 / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2006, v.27 no.3, pp.250-260
신원준 (경희대학교)
박영민 (경희대학교)
정동원 (경희대학교)
홍진우 (부산대학교)
선종주 (경희대학교)
이준우 (경희대학교)
정우상 (경희대학교)
박성우 (경희대학교)
문상관 (경희대학교)
박정미 (경희대학교)
고창남 (경희대학교)
조기호 (경희대학교)
김영석 (경희대학교)
배형섭 (경희대학교)
신원준, 박영민, 정동원, 홍진우, 선종주, 이준우, 정우상, 박성우, 문상관, 박정미, 고창남, 조기호, 김영석, & 배형섭. (2006). 뇌경색환자의 어혈변증과 동맥경직도의 관련성 연구. 대한한의학회지, 27(3), 250-260.
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Abstract

Backgrounds : Blood stasis is known as an important pathologic factor for vascular disorder in Oriental medicine. Despite of its clinical importance there has been few objective test for diagnosing blood stasis. Objectives : This study was designed to examine the relationship between blood stasis and arterial stiffness measured by cardio-ankle vascular index(CAVI). Methods : The subjects were 104 ischemic stroke patients with onset after 14 days. Their general characteristics, lipid profiles and uric acid were recorded. The degree of arterial stiffness was assessed by CAVI, and blood stasis was evaluated by diagnostic criteria. The data were analyzed by chi-square test, student t-test, spearman correlation analysis, and pearson correlation analysis. And then, stepwise multiple logistic regression analysis was applied in order to exclude the interactions among several factors. Results : There were significant differences in right, left and higher CAVI between blood stasis group and non blood stasis group(p-value<0.01). Age, systolic blood pressure, triglyceride and CAVI had relationships with blood static score. In multiple logistic regression analysis, the adjusted odds ratio of blood stasis for arterial stiffness with CAVI above 9 were 7.091(95% confidence interval, 1.641~30.638). Conclusions : The results demonstrated the relationship between blood stasis and arterial stiffness measured by CAVI. Therefore, we suggest that CAVI should be one of the objective tests for diagnosing blood stasis.

keywords
blood stasis, cardio-ankle vascular index(CAVI), arterial stiffness


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