- P-ISSN 1010-0695
- E-ISSN 2288-3339
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- P-ISSN1010-0695
- E-ISSN2288-3339
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Effect of LI4-LI11 Transcutaneous Electrical Nerve Stimulation on Regional Cerebral Blood Flow in Healthy Human Using SPECT and Statistical Parametric Mapping
Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2008, v.29 no.4, pp.205-212
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(2008). Effect of LI4-LI11 Transcutaneous Electrical Nerve Stimulation on Regional Cerebral Blood Flow in Healthy Human Using SPECT and Statistical Parametric Mapping. Journal of Korean Medicine, 29(4), 205-212.
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Abstract
Background and purpose: So far it was reported that acupuncture increased cerebral blood supply and stimulated the functional activity of brain nerve cells. A previous study demonstrated a correlation between LI4-11 electro-acupuncture (EA) and rCBF increase in frontal lobe. However, there remained a need to study further using various controls in acupuncture research. Transcutaneous electrical nerve stimulation (TENS) has been used as a non-invasive control in acupuncture study. This study was to evaluate the effect of LI4-LI11 TENS on regional cerebral blood flow (rCBF) in normal volunteers using single photon emission computed tomography (SPECT) and statistical parametric mapping (SPM). Methods: In the resting state, 99mTc-ECD brain SPECT scans were performed on 10 normal volunteers (9 males, 1 female, mean age 26.6±0.5 years; age range from 26 to 27 years). On the other day, 7 days after the resting examination, 15 minute TENS were applied at LI 4 and LI 11 on the right side of the subjects. Immediately after LI4-LI11 TENS, the second SPECT images were obtained in the same manner as the resting state. Significant increases and decreases of regional cerebral blood flow after LI4-LI11 TENS were estimated by comparing their SPECT images with those of the resting state using paired t statistics at every voxel, which were analyzed by statistical parametric mapping with a threshold of p = 0.001, uncorrected (extent threshold: k=100 voxels). Results: TENS applied at right LI4-LI11 increased rCBF in the left somatosensory association cortex (Brodmann area 5, 7). However there was no area where LI4-11 TENS decreased rCBF. Conclusion and suggestions: These results demonstrate that right LI4-LI11 TENS increased rCBF only in corresponding somatosensory association cortex, which was different from the previous results using LI4-11 EA. It is suggested that there be a different mechanism between TENS and EA.
- keywords
- Transcutaneous electrical nerve stimulation(TENS), LI4, LI11, regional cerebral blood flow, SPECT, SPM(statistical parametric mapping)
Reference
1
1. Omura, Y: Pathophysiology of acupuncture treat- ment: Effects of acupuncture on cardiovascular and nervous system. Acupuncture & Electro- Therapeutics Research. 1975;1(1):51-141.
2
2. 문상관, 김영석, 박성욱, 정우상, 고창남, 조기호, 배형섭, 이재동, 김덕윤. SPECT를 이용한 뇌경색환자의 건측 합곡-곡지 전침치료가 뇌관류에 미치는 영향. 대한침구학회지. 2004;21(1):111 -118.
3
3. Litscher G, Wang L, Yang NH, Schwarz G. Ultrasound-monitored efforts of acupuncture on brain and eye, Neurol Res. 1999;21:373-377.
4
4. Litscher G, Wang L, Yang NH, Schwarz G. Computer-controlled acupuncture Quantification and separation of specificeffects. Neurol Res. 1999;21:530-534.
5
5. Napadow V, Makris N, Liu J, Kettner NW, Kwong KK, Hui KKS, Effects of electroacupuncture versus manual acupuncture on the human brain as measured by fMRI. Human Brain Mapping. 2005;24:193-205.
6
6. 송호천, 범희승, 강화정, 안수기, 김성민, 정환정, 김지열. Tc-99m ECD 뇌혈류 SPECT를 이용한 백회, 인중, 합곡, 족삼리, 삼음교에서 체침의 뇌혈류에 대한 효과, 대한핵의학회지. 2000;34:456 -64.(794)
7
7. 김덕윤, 문상관, 이재성. Tc-99m ECD 뇌 SPECT를 이용한 합곡-곡지 전침 치료의 뇌혈류에 대한 효과, 대한핵의학회지. 2004;38(5):361.
8
8. Lee JD, Chon JS, Jeong HK, Kim HJ, Yun M, Kim DY, Kim DI, Park CI, Yoo HS. The cerebrovascular response to traditional acupu- ncture after stroke. Neuroradiology 2003, 45: 780-784.
9
9. Hsieh JC, Tu CH, Chen FP, Chen MC, Yeh TC, Cheng HC, Wu YT, Liu RS, Ho LT. Activation of the hypothalamus charaterizes the acupuncture stimulation at the analgesic point in human : a positron emission tomography study. Neurosci Lett. 2001;307(2):105-108.
10
10. 이호영, 이동수, 팽진철, 오창완, 조맹제, 정준기, 이명철. 뇌혈관 협착 환자에서 SPM과 확률뇌지도를 이용한 기저/아세타졸아미드 SPECT의 정량적 분석법의 유용성. 대한핵의학회지 2002;36 (6):357-367.
11
11. 이재성, 이동수, 이상건, 남현우, 김석기, 박광석, 정재민, 정준기, 이명철. H215O 양전자단층촬영술을 이용한 뇌기능 지도 작성(Ⅱ): 작업 기억의 지도 작성. 대한핵의학회지 1998;32(3):238-249.
12
12. 한진안, 문상관, 정동원, 배형섭, 박성욱, 정우상, 박정미, 고창남, 조기호, 김영석, 김덕윤. 양릉천-현종 전침치료가 뇌경색환자 및 정상인의 뇌혈류에 미치는 영향 -Brain SPECT와 SPM을 이용하여-．대한한의학회지. 2006;27(3):689-702.
13
13. 류종만, 문상관, 김영석, 박성욱, 정우상, 고창남, 조기호, 배형섭, 김덕윤. 합곡-곡지 전침치료가 정상인의 뇌혈류에 미치는 영향 -Brain SPECT와 SPM을 이용하여-．대한한의학회지. 2006;27(2) :276-283.
14
14. Langevin HM, Hammerschlag R, Lao L, Napa- dow V, Schnyer RN, Sherman KJ. Controversies in acupuncture research: Selection of controls and outcome measures in acupuncture clinical trials. The Journal of Alternative and Complem- entary Medicine. 2006;12(10):943-953.
15
15. 조재흥, 정석희, 이종수, 김성수. 전침과 경근 저주파의 경직 완화 효과에 대한 경근전도 분석. 한방재활의학과학회지. 2006;16(2):131-143.
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