- P-ISSN 1010-0695
- E-ISSN 2288-3339
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- P-ISSN1010-0695
- E-ISSN2288-3339
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Inhibitory Effect of Respective Herbs in Cheonggugamrosu on Oral Malodor Using Malodor Modeling of the Salivary Sediment System
Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2009, v.30 no.2, pp.79-87
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(2009). Inhibitory Effect of Respective Herbs in Cheonggugamrosu on Oral Malodor Using Malodor Modeling of the Salivary Sediment System. Journal of Korean Medicine, 30(2), 79-87.
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Abstract
Objective:This study assessed five respective herbs in Cheonggugamrosu (CGGRS) for ability to inhibit malodor in vitro. Methods:We used malodor modeling of the salivary sediment system. Incubation mixtures were prepared with sediment at 16.7% (v/v), amino acids (cysteine and tryptophan) at 6mM and either herb extract at 1% (w/v) or water as control. Mixtures were incubated at 37℃ and odor was monitored organoleptically and for volatile sulfur compounds with the Halimeter. Indole/skatole was determined by Kovac's colorimetric method. Results:Two of the herbs, Caryophilli Flos and Glycyrrhizae Radix, had inhibitory effect on malodor generation. Both of them significantly reduced VSC, organoleptic odor and indole/skatole formation (p<0.05). Conclusions:We found Caryophilli Flos and Glycyrrhizae Radix played a main role in CGGRS. Both herbs have potential as effective anti-malodor agents and this suggests they are worthy of further exploration.
- keywords
- oral malodor, salivary sediment system, Cheonggugamrosu, Caryophilli Flos, Glycyrrhizae Radix
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