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  • P-ISSN 1010-0695
  • E-ISSN 2288-3339

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加味逍遙散이 가임기 난소기능저하 불임여성의 난소기능개선에 미치는 영향에 관한 후향적 연구

A Retrospective Study on the Influence of Kamisoyo-san (Jiaweixiaoyao-san) on Improving Ovarian Function in Child-bearing Period Infertile Women with Ovarian Dysfunction

대한한의학회지 / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2009, v.30 no.5, pp.137-145
이한성 (경희대학교)
안광석 (경희대학교)
심범상 (경희대학교)
김성훈 (경희대학교)
최승훈 (경희대학교)
정윤재 (가천의과학대학교)
안규석 (경희대학교)
조광호 (자연담은 한의원)
김태경 (자연담은 한의원)
김춘환 (자연담은 한의원)
안수정 (자연담은 한의원)
이한성, 안광석, 심범상, 김성훈, 최승훈, 정윤재, 안규석, 조광호, 김태경, 김춘환, & 안수정. (2009). 加味逍遙散이 가임기 난소기능저하 불임여성의 난소기능개선에 미치는 영향에 관한 후향적 연구. 대한한의학회지, 30(5), 137-145.
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Abstract

Objectives:This study was performed to elicit the effectiveness of a herbal formula, Kamisoyo-san (Jiaweixiaoyao- san) on enhancing ovarian function in infertile woman with ovarian dysfunction. Methods:28 patients who initially visited between November 2006 and February 2009 and were administered Kamisoyo-san until May 2009 were retrospectively evaluated for their ovarian function by means of basal FSH (b-FSH), menstrual cycle, body mass index (BMI), and body fat ratio. To identify the major factor of improving ovarian function, 28 patients were classified into two groups by criteria of patent factors, such as pre-administration b-FSH, patient age, and treatment duration, respectively. Two groups were compared in terms of pregnancy percentage, b-FSH, menstrual cycle, BMI, and body fat ratio. Results:Post-administration b-FSH significantly decreased in comparison with pre-administration (p=0.004). The higher group (b-FSH ≥ 25mIU/mL) in pre-administration b-FSH was more effective in decrease of post-administration b-FSH than the lower one (10mIU/mL < b-FSH < 25mIU/mL). Conclusion:Kamisoyo-san may have a therapeutic effect on the infertility of child bearing period woman with ovarian dysfunction.

keywords
infertility, ovarian function, Kamisoyo-san (Jiaweixiaoyao-san), basal FSH


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