1 김덕곤 편저. 동의간질학. 서울:서원당. 1998:23-8, 77-91, 107-116, 291-309.

2 안효섭. 소아과학 제8판. 서울:대한교과서(주).2005:1060-75.

3 Na WK, Han KH, Lee HJ, Park EJ. A case report of epileptic children. The journal of Korean Oriental Pediatrics. 2004;18(1):131-8.

4 임종국. 침구치료학. 서울:집문당. 2001:333.

5 Sin DH, Jo ML. Experimental Study of Dadun (LR1), Shaofu(HT8) Reduction in Acupuncture on the Improvement of Cerebral Hemodynamics. The journal of Korean acupuncture & moxibustion society. 2004;21(1):33-50.

6 Sin JC, Yu CL, Jo ML. Effects of Xingjian(LR2), Shaofu(HT8) by Reinforcing and Reducing on the Regional Cerebral Blood Flow and Mean Arterial Blood Pressure in Normal Rats. The journal of Korean acupuncture & moxibustion society. 2003;20(6):190-200.

7 Park EJ, Cho MR. Experimental Study of Dadun(LR1), Shaochung(HT9), Shaofu (HT8) Reinforcement in Acupuncture on the Improvement of Cerebral Hemodynamics. The journal of Korean acupuncture & moxibustion society. 2007;24(1):111-25.

8 Kim JS, Hwang K, Bae KT, Nam SS, Kim YS. Effect of Acupuncture for Mental Stress on Short-term Analysis of Heart Rate Variability (HRV). The journal of Korean acupuncture & moxibustion society. 2004;21(5):227-39.

9 김덕곤, 김윤희, 김장현, 박은정, 백정한, 이승연 외. 동의소아과학. 서울:도서출판 정담. 2002:365-405.

10 Woo HS, Lee JD, Kim CH. The Effects of electroacupuncture stimuli to the Doublecortin and PSA-NCAM positive cells in the Dentate Gyrus of spontaneously hypertensive rats. The journal of Korean acupuncture & moxibustion society. 2003;20(2):123-34.

11 전국한의과대학 침구, 경혈학교실 편저. 침구학.서울:집문당. 1994:53-8.

12 Sohn YJ, Won R, Jung HS, Kim YS, Park YB, Sohn NW. 2 - DG Autoradiographic Imaging of Brain Activity Patterns by Electroacupuncture Stimulation in Awake Rats. The journal of Korean acupuncture & moxibustion society. 2001;18(3):56-68.

13 Park JB, Park HJ, Lee HJ. The methodological study of the change of Brain activity with acupoint stimulation using functional MHI -- focusing on visual areas. The journal of Korean acupuncture & moxibustion society. 1997;14(1): 266-72.

14 Cho ZH, Chung SC, Jones JP, Park JB, Park HJ, Lee HJ, et al. New findings of the correlation between acupoints and corresponding brain cortices using functional MRI. Proc, Natl, Acad, Sci, USA. 1998;95(5):2670-3.

15 Kim CH, Kim YS, Huh YB, Yoo JH. Effect of electroacupuncture on NADPH - diaphorase and neuropeptide Y neurons in cerebral cortex of SHR rats. The journal of Korean acupuncture & moxibustion society. 1999;16(4):283-91.

16 Kim JI, Kim YS, Kim CH. Difference in NOS between 2Hz and 100Hz EA in cerebral cortex , brain stem and cerebellum of spontaneously hypertensive rats. The journal of Korean acupuncture & moxibustion society. 2001;18(4): 116-24.

17 Jeong IG, Lee JD, Kim CH. Effect of Joksamni combination on NADPH- diaphorase, neuronal Nitric Oxide Synthase, Neuropeptide Y and Vasoactive Intestinal Peptide in the cerebral cortex of Spontaneously Hypertensive Rat. The journal of Korean acupuncture & moxibustion society. 2003;20(5):118-32.

18 Lee HM, Kim CH, Kim YS. Acupoint combinationrelated changes of NADPH-d diaphorase and neuronal nitric oxide synthase in the brainstem and cerebellum of spontaneously hypertensive rats. The journal of Korean acupuncture & moxibustion society. 2003;20(6):148-59.

19 Kim JD, Kang SK, Kim CH. The effects of acupuncture on NADPH- diaphorase and nNOS in the brain stem and cerebellum of SHR. The journal of Korean acupuncture & moxibustion society. 2004;21(5):1-12.

20 Kim DH, Nam SS, Kim CH. Effect of Electroacupuncture Stimulation on Activity of Neuronal NOS in Rats. The journal of Korean acupuncture & moxibustion society. 2006;23(5): 199-206.

21 Kim EH, Kim YJ, Lee HJ, Huh YB, Chung JH, Seo JC, et al. Acupuncture increases cell proliferation in dentate gyrus after transient global ischemia in gerbils. Neuroscience Letters.2001;297(1):21-4.

22 Park JH, Lee JD, Kim CH. Effects of Acupuncture and Electroacupuncture on the Doublecortin, PSA-NCAM and pCREB Expression in the Brain of Spontaneously Hypertensive Rats. The journal of Korean acupuncture & moxibustion society. 2004;21(3):61-81.

23 Park HJ, Lim S, Lee HS, Lee HJ, Yoo YM, Lee HJ, et al. Acupuncture enhances cell proliferation in dentate gyrus of maternally-separated rats. Neuroscience Letters. 2002;319:153-6.

24 Park HJ, Lim S, Joo WS, Yin CS, Lee HS, Lee HJ, et al. Acupuncture events 6-hydroxydopamineinduced neuronal death in the nigrostriatal dopaminergic system in the rat Parkinson's disease model. Experimental Neurology. 2003;180:92-7.

25 Kang JM, Park HJ, Choi YG, Choe IH, Park JH, Kim YS, et al. Acupuncture inhibits microglial activation and inflammatory events in the MPTPinduced mouse model. BRIAN RESEARCH. 2007;1131:211-9.

26 Liang XB, Liu XY, Li FQ, Luo Y, Lu J, Zhang WM, et al. Long-term high-frequency electroacupuncture stimulation prevents neuronal degeneration and up-regulates BDNF mRNA in the substantia nigra and ventral tegmental area following medial forebrain bundle axotomy. Molecular Brain Research. 2002;108:51-9.

27 Jang MH, Shin MC, Lee TH, Lim BV, Shin MS, Min BI, et al. Acupuncture suppresses ischemiainduced increase in c-Fos expression and apoptosis in the hippocampal CA1 region in gerbils. Neuroscience Letters. 2003;347:72-5.

28 Liu J, Cheng J. Changes of amino acids release in rat's hippocampus during kainic acid induced epilepsy and acupuncture. Acupuncture Research. 1995;20(3):50-4.

29 Jin HB, Li B, Gu J, Cheng JS, Yang R. Electro-acupuncture improves epileptic seizures induced by kainic acid in taurine-depletion rats. Acupuncture Electrotherapy Research. 2005;30 (3-4):207-17.

30 Lee EJ, Kim JW, Kwak MJ, Han SM, Lee JH, Hong HN, et al. Protective Effect of Etomidate on Kainic Acid-induced Neurotoxicity in Rat Hippocampus. The Journal of the Korean of anesthesiologists. 2001;40:794-801.

31 Oh YC, Lee MK, Kim JY. Convulsion and Neurodegeneration by Kainin Acid are Related to N-Methyl-D-Aspartate Receptor. The Kyungpook university medical journal. 1993;34(2):107-15.

32 Lee SH, Seo JB, Lee HS. The effect of nimodipine in preventing the hippocampal neuronal death caused by kainic acid-induced seizures. Chungbuk medical journal. 2000;10(1):13-9.

33 Jessica PM, Oswald S. Comparison of seizure phenotype and neurodegeneration induced by systemic kainic acid in inbred, outbred, and hybrid mouse strains. European Journal of Neuroscience. 2006;24:2191-2202.

34 Krisztina M, Federico M, Michaela E, Matthias E, Heike B, Ruth W, et al. The endocannabinoid system controls key epileptogenic circuits in the hippocampus. Neuron. 2006;51:455-66.

35 Massimo R, Silvio C, Giovanni G, Cristina R, Jan AG, Eleonora A, et al. Limbic seizures induce P-glycoprotein in rodent brain : functional implications for pharmacoresistance. The Journal of Neuroscience. 2002;22(14):5833-9.

36 조계선. 생쥐 해마에서 kainic acid에 의한 세포사유발 후 interleukin-18, -1$\beta$ 및 caspase-1의 발현에 대한 연구[박사학위논문]. 서울: 서울대학교 대학원. 2004.

37 이계훈. 편도핵내로 투여한 kainic acid에 의한 해 마의 손상에서 R-PIA의 전처치가 vimentin 및 GFAP의 면역조직반응변화에 미치는 영향에 관 한 연구[박사학위논문]. 서울: 한양대학교대학 원. 1998.

38 Sola C, Tusell JM, Serratosa J. Calmodulin is espressed by reactive microglia in the hippocampus of kainic acid-treated mice. Neuroscience. 1997;81(3):699-705.

39 Caterina B, Filippo G, Massimo T, Rosario S, Warren DH. Differential expression of S$100{\beta}$ and glial fibrillary acid protein in the hippocampus after kainic acid-induced lesions and mossy fiber sprouting in adult rat. Experimental Neurology.2000;161:317-29.

40 Shin HJ, Lee JY, Son EY, Lee DH, Kim HJ, Kang SS, et al. Curcumin attenuates the kainic acid-induced hippocampal cell death in the mice. Neuroscience Letters. 2007;416:49-54.

41 Massimo R, Carlo P, Marisa A, Cristina R, Teresa R, Daniele C, et al. Glia activation and cytokine increase in rat hippocampus by kainic acid-induced status epilepticus during postnatal development. Neurobiology of Disease. 2003; 14:494-503.

42 Teresa R, Massimo R, Carlo P, Cristina R, Jana V, Solomon LM, et al. Inflammatory response and glia activation in developing rat hippocampus after status epilepticus. Epilepsia. 2005;46(5): 113-7.

43 Lee HK, Choi SS, Han EJ, Lee JY, Kwon MS, Shim EJ, et al. Role of nicotinic acetylcholine receptors in the regulation of kainic acid-induced hippocampal cell death in mice. Brain Research Bulletin. 2004;64:309-17.

44 Duan RS, Chen Z, Dou YC, Hernan CQ, Inger N, Abdu A, et al. Apolipoprotein E deficiency increased microglial activation/CCR3 expression and hippocampal damage in kainic acid exposed mice. Experimental Neurology. 2006;202:373-80.

45 Eun SY, Hong YH, Kim EH, Jeon HJ, Suh YH, Lee JE, et al. Glutamate receptor-mediated regulation of c-fox expression in cultured microglia. BBRC. 2004;325:320-7.

46 Sanae H, Masahiro Y, Hiroshi N, Masayoshi M, Kensaku M. Enhanced cell-to-cell contacts between activated microglia and pyramidal cell dentrites following kainic acid-induced neruotoxicity in the hippocampus. Journal of Neuroimmunology. 2007;186:75-85.

47 Tamiwaki Y, Kato M, Araki T, Kobayoshi T. Microglial activation by epileptic activation through the propagation pathway of kainic acid-induced hippocampal seizures in the rat. Neuroscience Letters. 1996;217:29-32.

48 Hiroyuki M, Katsuaki S, Norio M, Osamu Y. Occurrence of complement protein C3 in dying pyramidal neurons in rat hippocampus after systemic administration of kainic acid. Neuroscience Letters. 2006;409:35-40.

49 Ryu SY, Kim JS, Choi YB, Han SR, Park JW, Park SK, et al. The Effect of 1,25-Dihydroxyvitamin D3 on Dopaminergic Neurons and Microglial Activation in Parkinsonian Rat Model Induced by 6-Hydroxydopamine. Journal of the Korean neurological association. 2005;23(3):368-73.