- P-ISSN 1010-0695
- E-ISSN 2288-3339
- Log In/Sign Up
- P-ISSN1010-0695
- E-ISSN2288-3339
Article Detail
Home > Article Detail
A Case of Non-alcoholic Steatohepatitis Treated with Herbal Medicine
Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2011, v.32 no.3, pp.50-54
(2011). A Case of Non-alcoholic Steatohepatitis Treated with Herbal Medicine. Journal of Korean Medicine, 32(3), 50-54.
- Downloaded
- Viewed
Abstract
Objective: To understand the characteristic of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), and study the traditional Korean medicine (TKM)-based strategies or therapeutics for them. Methods: A male patient with NASH was treated with only Oriental therapies, and then the clinical outcome was evaluated by serum biochemical parameters and radiographs. Result: The clinical and biochemical values of the patient fluctuated over three years according to the treatments and cessation of herbal medicines. Conclusion: NASH or NAFLD are now prevalent and these disorders could be targets of TKM, and this case report would provide useful information.
- keywords
- non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, traditional Korean medicine, herbal medicine, Objective: To understand the characteristic of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH), and study the traditional Korean medicine (TKM)-based strategies or therapeutics for them. Methods: A male patient with NASH was treated with only Oriental therapies, and then the clinical outcome was evaluated by serum biochemical parameters and radiographs. Result: The clinical and biochemical values of the patient fluctuated over three years according to the treatments and cessation of herbal medicines. Conclusion: NASH or NAFLD are now prevalent and these disorders could be targets of TKM, and this case report would provide useful information.
Reference
1
1. Adams LA, Angulo P. Treatment of nonalcoholic fatty liver disease. Postgrad Med J. 2006; 82(967):315-22.
2
2. Farrell GC, Chitturi S, Lau GK, Sollano JD. Guidelines for the assessment and management of non-alcoholic fatty liver disease in the Asia-Pacific region: executive summary. J Gastroenterol Hepatol. 2007; 22(6):775-7.
3
3. Clark JM, Diehl AM. Nonalcoholic fatty liver disease: an underrecognized cause of cryptogenic cirrhosis. JAMA, 2003; 289 (22): 3000-4.
4
4. Chavez-Tapia NN, Uribe M, Ponciano- Rodríguez G, Medina-Santillán R, Méndez- Sánchez N. New insights into the pathophysiology of nonalcoholic fatty liver disease. Ann Hepatol. 2009; 8:S9-S17.
5
5. Abrams GA, Kunde SS, Lazenby AJ, Clements RH. Portal fibrosis and hepatic steatosis in morbidly obese subjects: a spectrum of nonalcoholic fatty liver disease. Hepatology. 2004; 40:475-83.
6
6. Neuschwander-Tetri BA. Lifestyle modification as the primary treatment of NASH. Clin Liver Dis. 2009; 13(4):649-65.
7
7. Larter CZ, Chitturi S, Heydet D, Farrell GC. A fresh look at NASH pathogenesis. Part 1: the metabolic movers. J Gastroenterol Hepatol. 2010 Apr; 25(4):672-90.
8
8. Golovanova EV, Vinnitskaia EV, Shaposhnikova NA, Petrakov AV, Mel’kina ES. Effectiveness of the new plant hepatoprotector--Ropren in patients with non-alcoholic steatohepatitis. Eksp Klin Gastroenterol. 2010; (7):97-102.
9
9. Jaeschke H, Williams CD, McGill MR, Farhood A. Herbal extracts as hepatoprotectants against acetaminophen hepatotoxicity. World J Gastroenterol. 2010; 16(19):2448-50.
10
10. Chien CF, Wu YT, Tsai TH. Biological analysis of herbal medicines used for the treatment of liver diseases. Biomed Chromatogr. 2011; 25(1-2):21-38.
11
11. Açikel M, Sunay S, Koplay M, Gündoğdu F, Karakelleoğlu S. Evaluation of ultrasonographic fatty liver and severity of coronary atherosclerosis, and obesity in patients undergoing coronary angiography. Anadolu Kardiyol Derg. 2009; 9(4):273-9.
12
12. Newton JL, Pairman J, Wilton K, Jones DE, Day C. Fatigue and autonomic dysfunction in non-alcoholic fatty liver disease. Clin Auton Res. 2009; 19(6):319-26.
13
13. Alazmi WM, Regev A, Molina EG, Schiff ER. Predictors of cirrhosis in Hispanic patients with nonalcoholic steatohepatitis. Dig Dis Sci. 2006; 51(10):1725-9.
14
14. Powell EE, Cooksley WG, Hanson R, Searle J, Halliday JW, Powell LW. The natural history of nonalcoholic steatohepatitis: a follow-up study of forty-two patients for up to 21 years. Hepatology. 1990; 11(1):74-80.
15
15. Adams LA, Feldstein AE. Nonalcoholic steatohepatitis: risk factors and diagnosis. Expert Rev Gastroenterol Hepatol. 2010; 4(5):623-35.
16
16. Marchesini G, Marzocchi R. Metabolic syndrome and NASH. Clin Liver Dis. 2007; 11(1):105-17.
17
17. Tsochatzis EA, Papatheodoridis GV. Smoking is associated with histological severity in nonalcoholic steatohepatitis. Hepatology. 2010; 52(4):1522-3.
18
18. Videla LA, Rodrigo R, Araya J, Poniachik J. Insulin resistance and oxidative stress interdependency in non-alcoholic fatty liver disease. Trends Mol Med. 2006; 12(12):555-8.
19
19. Petersen KF, Dufour S, Hariri A, Nelson- Williams C, Foo JN, Zhang XM, et al. Apolipoprotein C3 gene variants in nonalcoholic fatty liver disease. N Engl J Med. 2010; 362(12):1082-9.
20
20. Carulli L, Canedi I, Rondinella S, Lombardini S, Ganazzi D, Fargion S, et al. Genetic polymorphisms in non-alcoholic fatty liver disease: interleukin-6-174G/C polymorphism is associated with non-alcoholic steatohepatitis. Dig Liver Dis. 2009; 41(11):823-8.
21
21. Malínská H, Oliyarnyk O, Hubová M, Zídek V, Landa V, Simáková M, et al. Increased liver oxidative stress and altered PUFA metabolism precede development of non-alcoholic steatohepatitis in SREBP-1a transgenic spontaneously hypertensive rats with genetic predisposition to hepatic steatosis. Mol Cell Biochem. 2010; 335(1-2): 119-25.
22
22. Caldwell S, Lazo M. Is exercise an effective treatment for NASH? Knowns and unknowns. Ann Hepatol. 2009; 8 Suppl 1:S60-6.
23
23. Haddad Y, Vallerand D, Brault A, Haddad PS. Antioxidant and Hepatoprotective Effects of Silibinin in a Rat Model of Nonalcoholic Steatohepatitis. Evid Based Complement Alternat Med. 2009. Epub ahead of print.
24
24. Kim SH, Lee JH, Jung YJ, Choi MY, Kim YC, Woo HJ. A Case of Nonalcoholic Steatohepatitis in a child patient. Korean J. Orient. Int. 2010; 31(2):1106-10.
25
25. Hu XP, Shin JW, Wang JH, Cho JH, Son JY, Cho CK, et al. Antioxidative and hepatoprotective effect of CGX, an herbal medicine, against toxic acute injury in mice. J Ethnopharmacol. 2008; 120(1):51-5.
26
26. Wang JH, Shin JW, Son JY, Cho JH, Son CG. Antifibrotic effects of CGX, a traditional herbal formula, and its mechanisms in rats. J Ethnopharmacol. 2010; 127(2):534-42.
- Downloaded
- Viewed
- 0KCI Citations
- 0WOS Citations
Other articles from this issue
- Anatomical Observation on Components Related to Foot Gworeum Meridian Muscle in Human
- Broussonetia kazinoki Siebold stimulates immune response in ovalbumin-immunized mice
- Single Oral Dose Toxicity Evaluation of Leejung-tang, a Korean Traditional Herbal Formula, in Crl:CD (SD) rats
- Evaluation of the Immune-Stimulating Activity of Samul-tang, a Traditional Korean Herbal Medicine, Standardized by HPLC-PDA
- Screening of β-Catenin/TCF Transcription Factor Inhibitors in Medicinal Herb Extracts
- Overview of RCT for Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis
- A Case of Non-alcoholic Steatohepatitis Treated with Herbal Medicine
- more
Recommanded Articles
This website recommended the use the Chrome browser for journal website.