논문 상세

Home > 논문 상세
  • P-ISSN 1010-0695
  • E-ISSN 2288-3339

黃芩으로 인한 간손상으로 판단되는 건선 환자 1례 보고

A Psoriasis Case Report on Liver Damage Related to Scutellaria Radix

대한한의학회지 / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2011, v.32 no.4, pp.149-158
이기훈 (강남동약한의원)
양지은 (강남동약한의원)
장규태 (경희대학교)
  • 다운로드 수
  • 조회수

Abstract

Object: Any medication can have the risk of liver damage. To prevent this risk, liver function tests should be monitored carefully during every course of medication. This paper is a psoriasis case report on liver damage related to Scutellaria Radix medication. Shown by this case, herbal medicine has the possibility of liver damage, too. Therefore it should be carefully used under the direction of Oriental Medical Doctors who specialize in it. The purpose of this case report is to suggest this, and that more cases of liver damage related to herbal medicine should be reported. Methods: To monitor the medication’s effect on the liver, liver function was evaluated during medications. Reflotron plus was used to evaluate AST and ALT by analyzing peripheral blood. Results: By this test, a case was identified as liver damage caused by a medication including Scutellaria Radix. Conclusion: This case suggests that Scutellaria Radix medication caused liver damage in a certain patient. Therefore,to prevent liver damage related to Scutellaria Radix, doctors should monitor patient's liver function regularly.

keywords
liver damage, Scutellaria Radix, liver function, psoriasis, hepatic toxicity


참고문헌

1

1. Korean Dermatology Association. Dermatology (5th ed.). Seoul:Ryo Moon Gak.P.Co. 2008:241.

2

2. Youn JI. Psoriasis Clinic. Seoul:Designmeca. 2004:102.

3

3. Youn JI. Etiology & Treatment of Psoriasis Update. Seoul:Designmeca. 2006:7-8.

4

4. Yoo JW, Park SD. Effect of Whaganjeon on the hepatoxicity of carbon tetrachloride in rats. The journal of Dong Guk Oriental Medicine. 1995; 4(3):313-325.

5

5. Byun BH, Seo BI. Molecular Celll Biological Study on Rat Hepatocytes Cytotoxicity and DNA Synthesis Effects of Scutellariae Baicalensis Radix Herbal acupuncture Solution(SBRHA). Kor. J. Herbology. 2004;19(1):35-40.

6

6. Byun BH, Seo BI. Safety study on Acute Toxicity of Scutellariae Baicalensis Radix Herbal acupuncture Solution(SBRHA). Kor. J. Herbology. 2003;18(4):47-51.

7

7. Lee JS, Lee SD. Effects of Liver Function on Blood of Drug Users(Herbal and Western) in Koreans. Kor. J. Oriental Preventive Medical Society. 2004;8(1):59-74.

8

8. Youn JI. Etiology & Treatment of Psoriasis. Seoul:Korea Medical Book Co. 1996:15-27, 30-148, 131-3.

9

9. Yeom YH, Kim JE. Bokjin and Truth of Prescription. Gangwon:Euibang P.Co. 2007: 654-655, 657-659.

10

10. Hwong DY. Jeungmaek Bangyakhapyeon. Seoul: Namsandang. 1992:122-123.

11

11. Lee SD. Prescriptionology fo Oriental Medicine, Seoul:Yeogang P.Co. 1994:228.

12

12. Kown HO. Evaluation Method on Toxicity of Extract of Rheum palmatum through Single Blinded Study. Dongeui University. Doctoral Degree 2009.

13

13. Felix S., Gerlinde E., Helmut K. S. Hepatotoxicity of botanicals. Public Health nutrition. 2000;3(2): 113-124.

14

14. Kang SH, Kim JI, Jeong KH, Ko KH, Ko PG, Hwang SW, et al. Clinical characteristics of 159 cases of acute toxic hepatitis. The Korean Journal of Hepatology. 2008;14:483-492.

15

15. Lee WY, Park BC, Kim HS, Joung KO, Yoon SI, Kwon SK, et al. A case of acute interstitial nephropathy and toxic hepatitis after short-term herbal medication. The Korean Journal of Medicine. 2007;73(1):103-106.

16

16. Seo JC, Jeon WJ, Park SS, Kim SH, Lee KM, Chae HB, et al. Clinical Experience of 48 Acute Toxic Hepatitis Patients. 2006;12(1):74-81.

17

17. Yoon YK, Han SS, Yoo JY, Chou LS, Koo BS. A Clinical Study about Effect of Long Term Herb Medication on Liver Function. J. of. Oriental Chr. Dis. 2002;8(1):30-34.

18

18. Kim DW, Lee UJ, An IH, Ban JS, Ryu CY, Lee SM. A study on the effect of prolonged administration of different oriental medicines on the liver function. J Korean Oriental Med. 1993;14(2): 245-253.

19

19. Kang BS, Kim IR, Kim HC, Choi HY, Lee YJ. Herbology. Seoul:Younglimsa.1999:178-179.

20

20. Ha KT, Jeong SS, Kim CH, Choi DY, Kim JK. Study on the Hepatoprotective Effect and Cytochrome P450 Regulation of Scutellaria Radix. Korean J. Oriental Physiology & Pathology. 2008;22(1):155-161.

상단으로 이동

대한한의학회지