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  • P-ISSN 1010-0695
  • E-ISSN 2288-3339

The Effect of Mild Cognitive Impairment Management Program on Traditional Korean Medicine in a Public Health Center

Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2013, v.34 no.3, pp.106-118


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Abstract

Objectives: The aim of this study was to evaluate the effect of a mild cognitive impairment (MCI) management program on traditional Korean medicine in a public health center. Methods: In order to examine the effect of the MCI management program, we investigated MCI patients who participated in the program. MCI patients were treated with Jodeung-san (JDS) or Dangguijagyag-san (DGJYS) for 6 weeks. Mini Mental State Examination-Dementia Screening (MMSE-DS), Geriatric Quality of Life-Dementia (GQOL-D), Geriatric Depression Scale in Korea (GDS-K), and biochemical examination of blood were conducted at intervals of 6 weeks. A satisfaction survey was collected after this program. Results: MMSE-DS mean score increased significantly, by 4.09 (p=0.000) in the JDS group and by 4.15 (p=0.000) in the DGJYS group. GQOL-D mean score also increased significantly, by 5.90 (p=0.000) in the JDS group and by 5.07 (p=0.000) in the DGJYS group. GDS-K mean score decreased significantly, by 10.63 (p=0.000) in the JDS group and by 9.69 (p=0.000) in the DGJYS group. MMSE-DS, GDS-K and GQOL-D scores were not significantly different between the JDS and DGJYS groups. All of the participants were satisfied with the program, and 90% of the participants expressed a high intention to participate in the program again. Conclusions: Both Jodeung-san and Dangguijagyag-san treatment showed improvement on cognitive function, depression and quality of life in this program. Additional studies with more subjects will be required to prove credibility and validity more clearly.

keywords
Jodeung-san, Dangguijagyag-san, MCI, MMSE-DS, GDS-K, GQOL-D


Reference

1

1. Statistics Korea. Future Population Projection.Statistics Korea. 2012.

2

2. Ministry of Health & Welefare. Survey ofDementia Prevalence Rate. Ministry of Health &Welefare. 2008.

3

3. Ku BD, Kim SG, Lee JY, Park KH, Shin JH,Kim KK, et al. Clinical practice guideline for dementiaby Clinical Research Center for Dementiaof South Korea. J Korean Med Assoc. 2011;54(8):861-875.

4

4. Choi KG. Neuropathology of MCI-View fromRelationships with Aging and Alzheimer’sDisease-. Dementia and NeurocognitiveDisorders. 2003;2:101-107.

5

5. Petersen RC, Doody R, Kurz, Mohs RC, MorrisJC, Rabins PV, et al. Current Concepts in MildCognitive Impairment. Arch Neurol. 2001;58:1985-1992.

6

6. Petersen RC, Smith GE, Waring SC, Ivnik RJ,Tangalos EG, Kokmen E. Aging, memory, andmild cognitive impairment. Int Psychogeriatr.1997;9(1): 65-69.

7

7. Shah Y, Tangalos EG, Petersen RC. Mild cognitiveimpairment. When is it a precursor toAlzheimer's disease? Geriatrics. 2000;55:65-68.

8

8. Flicker C, Ferris SH, Reisberg B. Mild cognitiveimpairment in the eldery: predictiors of dementia.Neurology. 1991;41:1006-1009.

9

9. Ministry of Health & Welefare. NationalEpidemiologic Investigation. Ministry of Health& Welefare. 2008.

10

10. Han CS, Lee JY, Lee DW, Ryu SH, Lee KJ, KimJH, et al. Development of Hybrid Model forIntegrating Management of Geriatric Depressionand Dementia in Urban Area. J Korean GeriatrSo. 2006;10(2):104-114

11

11. John KA, Heather BB. The sensitivity of theBeck Depression Inventory to changes ofsymptomatology. Br J Psychiatry. 1974;125:184-185.

12

12. Peter, R. Ageing and the brain. Postgrad Med J.2007;82:84-88

13

13. Heo EJ, Kang JS, Kang HW, Jeon WK.Evaluation on the Quality of Research Field withTraditional Herbal Prescriptions for DementiaTherapy. J of Oriental Neuropsychiatry. 2012;23(1):93-114.

14

14. Murakami Y, Zhao Q, Harada K, Tohda M,Watanabe H, Matsumoto K. Choto-san, a Kampoformula, improves chronic cerebral hypo-perfusion-induced spatial learning deficit via stimulationof myscarinic M1 receptor.Pharmacology Biochemistry and Behavior.2005;81(3):616-625.

15

15. Koichi Y, Yutaka S, Etsuro H, Nobuyasu S,Hirozo G, Owao S, et al. Protective effects ofChoto-san and hooks and stems of Uncaria sinesisagainst delayed neuronal death after transientforebrain ischemia in gerbil. Phytomedicine.2004;11:478-489.

16

16. Watanabe H, Zhao Q, Matsumoto K, Tohda M,Murakami Y, Zhang SH, et al. Pharmacologicalevidence for antidementia effect of Chotosan(Guteng-san), a traditional Kampo medicine.Pharamacol Biochem Behav. 2003;75(3):635-643.

17

17. Mizushima Y, Kan S, Yoshida S, Irie Y, UrataY. Effect of Choto-san a Kampo medicine, onimpairment of passive avoidance performance insenescence accelerated mouse(SAM).Phytotherapy research. 2003;17:542-545.

18

18. Matsuoka T, Narumoto J, Shibata K, OkamuraA, Taniguchi S, Kitabayashi Y, et al. Effect ofToki-Shakuyaku-San on Regional CerebralBlood Flow in Patients with Mild CognitiveImpairment and Alzheimer’'s Disease. Evi-BasedCom and Alt Med. 2012.

19

19. Inanaga K, Dainoson K, Ninomiya Y, TAkii O,Omaru M, Tanaka T, et al. Effects ofToko-Shakuyaku-San in Patients with SenileCognitive Disoreders. Progress in Medicine.1996;16:293-300. 1996.

20

20. Iwasaki K, Satoh-Nakaqawa T, Maruyama M,Monma Y, Tomita N, Tanji H, et al. A randomized,observer-blind, controlled trial of the traditionalChinese medicine Yi-Gan San for improvementof behavioral and psychological symtomsand activities of daily living in dementiapatients. J Clin Psychiatry. 2005;66(2):248-252.

21

21. Folstein MF. Folstein SE. “Mini-Mental State":a practical method for grading the cognitive stateof patients for the clinician. J of Psych Res.1975;12:189-198.

22

22. Park JH, Kwon YC. Standardization of Koreanof the Mini-Mental State Examination(MMSE-K) for Use in the Elderly -Part II.Diagnostic Validity. J Korean NeuroPsychiatricAssoc. 1989;28: 508-513.

23

23. Kang YW, Na DY, Han SH. A Validity Studyon the Korean Mini-Mental State Examination(K-MMSE) in Dementia Patients. J KoreanNeurol Assoc. 1997;15:300-307.

24

24. Lee JH, Lee KU, Lee DY, Kim KW, Kim JH,Lee KH, et al. Development of the Korean versionof the consortium to establish a registry foralzheimer’s disease assessment packet (CERAD-K): clinical and neuro-psychological assessmentbatteries. J Gerontology Series B: PsychologicalSciences and Social Sciences. 2002;57(1):47-53.

25

25. Han JW, Kim TH, Joo JH, Park JH, Kim JR,Yoo SH, et al. A Normative Study of theMini-Mental State Examination for DementiaScreening (MMSE-DS) and Its Short form(SMMSE-DS) in the Korean Elderly. J KoreanGeriatr Psychiatry. 2010;14(1):27-37.

26

26. Lee HS, Kim JH, Ko HJ, Ku HM, Kwon EJ, ShinJY, et al. The Standardization of the GeriatricQuality of Life scale-Dementia(GQOL-D). JKorean Geriatr Soc. 2004;8(3):151-164.

27

27. Ki BS, Lee CW. A Preliminary Study for theStandardization of Geriatric Depression Scale inKorea. J Korean NeuroPsychiatric Assoc. 1995;129:1875-1885.

28

28. Ministry of Health & Welefare. Direction forKorean Medicine Health Promotion Program in2013. Ministry of Health & Welefare. 2012.

29

29. Gyeonggi Statistical Information Service.Population Statistics. Gyeonggi StatisticalInformation Service. 2012.

30

30. Choi SH, Na DL, Oh KM, Park BJ. A Short formof the Samsung Dementia Questionnaire(S-SDQ): development and cross-validation. JKorean Neurol Assoc. 1997;17(2):253-258.

31

31. Galasko D, Kauber MR, Hoftetter R, Salmon DP,Lasker B, Thal LJ. The mini-mental state examinationin the elderly diagnosis of Alzheimer’disease. Arch Neurol. 1990;47(1):49-52.

32

32. Clark CM, Sheppard L, Fillenbaum GG, GalaskoD, Morris, JC, Koss E, et al. Variability in annualMini-Mental State Examination score in patientswith probable Alzheimer disease: a clinical perspectiveof data from the Consortium to Establisha Registry for Alzheimer's Disease. Arch Neurol. 1999;56(7):857-862.

33

33. Lee KS, Jung HK, Oh BH, Hong CH.Comparison of the Validity of Screening Testsfor Dementia and Mild Cognitive Impairment ofthe Elderly in a Community K-MMSE,MMSE-K, MMSE-KC, and K-HDS. J KoreanNeuroPsychiatric Assoc. 2009;48(2):61-69.

34

34. Nasreddine ZS, Phillips NA, Beirian V,Charbonneau S, Whitehead V, Collin I, et al. TheMontreal Cognitive Assessment, MoCA: a briefscreening tool for mild cognitive impairment. JAmerican Geriatrics Society. 2005;53(4):695-699.

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