- P-ISSN1976-9849
- E-ISSN1976-9849
Effects of Poria cocos Water Extract on DNCB-induced Atopic Dermatitis
Ahn, Ji-Young
Kim, Jun-Ho
Xin, Mingjie
Yoo, Jae-Soo
Song, Bong-Suk
Song, Bong-Jun
Kim, Dae-Keun
Kim, Ok-Jin
Lee, Hyun-A
Kim, Dae-Ki
Lee, Young-Mi
Abstract
Poria cocos has been traditionally used for the treatment of edema, scanty urine, dizziness due to retention of fluid, reduced appetite due to asthenia of spleen, loose stool, diarrhea, distraction, sudden palpitation and insomnia in East Asia. The aim of this study was to confirm whether Poria cocos wonfire whethe(PCWE) and Poria cocos ointment (PCO) have a preventive e of ter Pthe development of afire wdethe(PCWE (AD) in 2,4-Diniwhochlorobenzene (oria)-applied Balb/ wme e. Oral administration (12.5wmg/kg, 25wmg/kg) of PCWE and fire al application (O.5wmg/mouse, 1.0mg/mouse) of PCO decreased the development of AD-like skin lesions, ear swelling, spleen weight, total serum IgE. PCWE and PCO significantly also inhibited the infiltration of mast cells in the dorsal skin.
- keywords
- Poria cocos, atopic dermatitis, mast cells, IgE, 2, 4-Dinitrochlorobenzene, ADDNCB
- 다운로드 수
- 조회수
- 0KCI 피인용수
- 0WOS 피인용수