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Low-grade osteosarcoma arising from cemento-ossifying fibroma: a case report

Journal of the Korean Association of Oral and Maxillofacial Surgeons / Journal of the Korean Association of Oral and Maxillofacial Surgeons, (P)2234-7550; (E)2234-5930
2015, v.41 no.1, pp.48-51
Yong Bin Lee (Yonsei University)
Nam-Kyoo Kim (Catholic Kwandong University International St. Mary’s Hospital)
(Gangnam Severance Hospital)
Hyung Jun Kim (Yonsei University)

Abstract

Cemento-ossifying fibromasare benign tumors, and, although cases of an aggressive type have been reported, no cases of cemento-ossifying fibromatransforming into osteosarcoma have been documented previously. Low-grade osteosarcoma is a rare type of primary bone tumor, representing 1%-2% of all osteosarcomas. A 45-year-old female patient was diagnosed with cemento-ossifying fibroma,treated with mass excision several times over a period of two years and eight months, and followed up. After biopsy gathered because of signs of recurrence, she was diagnosed with low-grade osteo-sarcoma. The patient underwent wide excision, segmental mandibulectomy, and reconstruction with fibulafree flap.The aim of this report is to raise awareness of the possibility that cemento-ossifying fibromacan transform into osteosarcoma and of the consequent necessity for careful diagnosis and treatment planning.

keywords
Cemento ossifying fibroma, Low-grade osteosarcom

Journal of the Korean Association of Oral and Maxillofacial Surgeons