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Spontaneous bone regeneration in resected non-continuous mandible due to medication-related osteonecrosis of the jaw

Journal of the Korean Association of Oral and Maxillofacial Surgeons / Journal of the Korean Association of Oral and Maxillofacial Surgeons, (P)2234-7550; (E)2234-5930
2021, v.47 no.6, pp.465-470
https://doi.org/10.5125/jkaoms.2021.47.6.465
Alparslan Esen (Necmettin Erbakan University)
Gokhan Gurses (Selcuk University, Konya, Turkey)
Sebnem Akkulah (Necmettin Erbakan University)

Abstract

Few cases of spontaneous bone regeneration after extensive resection of the jaw bone have been reported, but it is more common in young adults or children. In this case, we report spontaneous bone healing in a 73-year-old female patient. On radiological examination, necrotic regions were seen in the right mandible. She was diagnosed with medication-related osteonecrosis of the jaw due to previous bisphosphonate use. After segmental resection, stabilization achieved using a reconstruction plate. The periosteum was preserved during the procedure. Twelve months later, panoramic radiography was taken and bone formation was seen both horizontally and vertically around the plate. If the periosteum is preserved and stabilization is achieved after resection in benign lesions, the bone may regenerate spontaneously regardless of age. Therefore, instead of simultaneous autogenous bone ap-plication, such patients may be followed to determine whether spontaneous bone healing will occur. This should improve patient comfort and reduce surgical cost.

keywords
Osteonecrosis, Bone regeneration, Periosteum, Mandible

Journal of the Korean Association of Oral and Maxillofacial Surgeons