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  • 한국과학기술정보연구원(KISTI) 서울분원 대회의실(별관 3층)
  • 2024년 07월 03일(수) 13:30
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ISSN : 0376-4672

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59권 4호

5% NaF를 함유한 이중 고분자 접착필름의 물리·화학적 특성

Physical and chemical properties of double-layers adhesive polymer film supplemented with 5% NaF

지명관 (조선대학교 치과대학 소아치과학 교실)
이상호 (조선대학교 치과대학 소아치과학 교실)
이난영 (조선대학교 치과대학 소아치과학 교실)
대한치과의사협회지 / The Journal of the Korean Dental Association, (P)0376-4672; (E)2713-7961
2021, v.59 no.4, pp.204-212
https://doi.org/10.22974/jkda.2021.59.4.001
지명관, 이상호, & 이난영. (2021). 5% NaF를 함유한 이중 고분자 접착필름의 물리·화학적 특성. 대한치과의사협회지, 59(4), 204-212, https://doi.org/10.22974/jkda.2021.59.4.001

Abstract

Objective : To improve the remineralization effect of fluoride adhesion film, we developed a double-layers adhesive film, and then evaluate its physical properties and fluoride-releasing ability. Methods : The tensile strength, elongation, dissolution rate and fluoride-releasing capacity characteristics of the adhesive films were analyzed. Results : There was no variation in thickness among the adhesive films. The tensile strength was highest in the polyvinyl alcohol (PVA) adhesive film and lowest in the pullulan adhesive film. The elongation rate was highest in pullulan film, followed by PVA-pullulan film and PVA film. Compared with the PVA adhesive film, the double-layer adhesive film exhibited higher fluoride ion emission for up to 60 minutes. Adhesive films had greater fluoride ion emission than fluoride varnish after 6 hours of application. Conclusion : The tensile strength and elongation characteristics of double-layer adhesive films were superior to those of single-layer adhesive films. PVA-pullulan double-layer adhesive film had very high initial fluoride ion emission compared with PVA adhesive film and fluoride varnish. This increased fluoride ion emission may compensate for the disadvantages of fluoride varnish and PVA adhesive film. The above results indicate that the PVA-pullulan double-layer adhesive film has improved physical properties and fluoride-releasing capacity compared with conventional PVA adhesive film.

keywords
fluorides, polyvinyl alcohol, pullulan

참고문헌

1.

1. Chu CH, Lo E. Uses of sodium fluoride varnish in dental practice. Ann R Australas Coll Dent Surg 2008;19:58-61.

2.

2. Milgrom P, Taves DM, Kim AS, Watson GE, Horst JA. Pharmacokinetics of fluoride in toddlers after application of 5% sodium fluoride dental varnish. Pediatrics 2014;134(3):870-874.

3.

3. Berg J, Riedy CA, Tercero A. Patient and parental perception of a new fluoride varnish. Compend Contin Educ Dent. 2006;27(11):614-618.

4.

4. Eakle WS, Featherstone JD, Weintraub JA, Shain SG, Gansky SA. Salivary fluoride levels following application of fluoride varnish or fluoride rinse. Community Dent Oral Epidemiol. 2004;32(6):462-469.

5.

5. Kim MJ. Lee SH, Lee NY, Lee IH. Evaluation of the effect of PVA tape supplemented with 2.26% fluoride on enamel demineralization using microhardness assessment and scanning electron microscopy: In vitro study. Arch Oral Biol 2013;58:160-166.

6.

6. Lee SH, Lee NY, Lee IH. Clinical evaluation of the efficacy of fluoride adhesive tape (F-PVA) in reducing dentin hypersensitivity. Am J Dent 2013;26:143-148.

7.

7. Kim MR, Lee NY, Jih MK, Kim JW, Choi WS, Lee SH. Comparison of the re-mineralization effect of newly-developed fluoride agents according to the depth of early carious lesions. Oral Biology Research 2020;44(3):1-9.

8.

8. 김소영, 이상호, 이난영, 지명관. Silver diamine fluoride와 sodium fluoride (NaF) 바니쉬의 법랑질 인공우식병소 재광화 효과. 대한소아치과학회지2020;47(3):266-276.

9.

9. Al Dehailan L, Lippert F, González-Cabezas C, Eckert GJ, Martinez-Mier EA. Fluoride concentration in saliva and biofilm fluid following the application of three fluoride varnishes. J Dent 2017;60:87-93.

10.

10. Farris S, Unalan IU, Introzzi L, Fuentes-Alventosa JM, Cozzolino CA. Pullulan-based films and coatings for food packaging: Present applications, emerging opportunities, and future challenges. Appl Polym Sci 2014;131(13):1-12.

11.

11. Vuddanda PR, Montenegro-Nicolini M, Morales JO, Velaga S. Effect of plasticizers on the physico-mechanical properties of pullulan based pharmaceutical oral films. Eur J Pharm Sci 2017;96:290-298.

12.

12. Vila MM , Tardelli ER, Chaud MV, Tubino M, Balcão VM. Development of a buccal mucoadhesive film for fast dissolution: mathematical rationale, production and physicochemical characterization. Drug Deliv 2014;21(7):530-539.

13.

13. Zhang XF, Chen X, Pan L. Fluoride concentration in saliva after use of fluoride varnish. Shanghai Kou Qiang Yi Xue 2003;12:241-243.

14.

14. 박승효, 이상호, 이난영. 불소 테잎 적용 후 시간변화에 따른 타액 내 불소농도. 대한소아치과학회지 2009;36:377-383.

15.

15. Zero DT, Raubertas RF, Pedersen AM, Fu J, Hayes AL, Featherstone JD. Studies of Fluoride retention by oral soft tissues after the application of home-use topical fluorides. J Dent Res 1992;71:1546-1552.

16.

16. 이가영, 이상호, 이난영 : 폴리비닐알코올 기반 고분자 불소 함유 테이프의 구강내 불소 유리 성능 평가. 대한소아치과학회지 2013;40(2):89-97.

17.

17. Ghadermazi R, Hamdipour S, Sadeghi K, Ghadermazi R, Khosrowshahi Asl A. Effect of various additives on the properties of the films and coatings derived from hydroxypropyl methylcellulose-A review. Food Sci Nutr 2019;13;7(11):3363-3377.

18.

18. Prajapati VD, Chaudhari AM, Gandhi AK, Maheriya P. Pullulan based oral thin film formulation of zolmitriptan: Development and optimization using factorial design. Int J Biol Macromol 2018;107:2075-2085.

19.

19. Morales JO, McConville JT : Manufacture and characterization of mucoadhesive buccal films. Eur J Pharm Biopharm 2011;77(2):187-199.

20.

20. Sharma R, Kamboj S, Singh G, Rana V. Development of aprepitant loaded orally disintegrating films for enhanced pharmacokinetic performance. Eur J Pharm Sci 2016;84:55-69.

21.

21. Krull SM, Ma Z, Li M, Davé RN, Bilgili E. Preparation and characterization of fast dissolving pullulan films containing BCS class II drug nanoparticles for bioavailability enhancement. Drug Dev Ind Pharm 2016;42(7):1073-1085.

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