- P-ISSN 1010-0695
- E-ISSN 2288-3339
- Log In/Sign Up
- P-ISSN1010-0695
- E-ISSN2288-3339
Article Detail
Home > Article Detail
Neuroprotective Effect of Hyulbuchookau-tang on Global Cerebral Ischemia of the Rats
Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2007, v.28 no.2, pp.44-53
&
(2007). Neuroprotective Effect of Hyulbuchookau-tang on Global Cerebral Ischemia of the Rats. Journal of Korean Medicine, 28(2), 44-53.
- Downloaded
- Viewed
Abstract
Objectives : This study examined the neuroprotective effect of Hyulbuchookau-tang (血府逐瘀湯, HBCAT) against neural damage following global cerebral infarction. Methods : Sprague-Dawley rats were induced with global cerebral infarction by occlusion of the bilateral common carotid artery with hypotension (CCAO). The rats were divided into 3 groups. We treated extract of HBCAT to one group after operation (sample group), one group wasn't induced with ischemic damage after operation (sham group), and one group was induced with ischemic damage after operation (control group) but not treated. We observed neurological scores and cresyl violet-stained hippocampus CA1 area, TUNEL-positive neurons, and Bax-positive neurons in brain regions. Results : HBCAT treatment after CCAO increased pyramidal neurons in CA1 hippocampus induced by CCAO. HBCAT treatment after CCAO reduced Bax-positive neurons in CA1 hippocampus of brain regions induced by CCAO. HBCAT treatment after CCAO wasn't effective for HSP70-positive neurons in CA1 hippocampus induced by CCAO. Conclusions : These results suggest that HBCAT has a neuroprotective effect against global cerebral ischemia.
- keywords
- : Hyulbuchookau-tang (血府逐瘀湯, HBCAT), common carotid artery occlusion (CCAO), neuroprotective effect, global cerebral infarction, : Hyulbuchookau-tang (血府逐瘀湯, HBCAT), common carotid artery occlusion (CCAO), neuroprotective effect, global cerebral infarction
- Downloaded
- Viewed
- 0KCI Citations
- 0WOS Citations
Other articles from this issue
- Neuroprotective Effect of Gagamchongmyung-tang on the Deficits of Learning and Memory by MCAO in the Rat
- Clinical Characteristics of Patients with Halitosis
- Study on Association of DSOM Items for Uterine Myoma in Oriental Medicine -Control Group:Outpatient and Clinical Trials Data-
- A Clinical Study about the Effect of Soshiho-tang on a Case of Parkinson's Disease with Pontine Infarction
- Neuroprotective Effect of Hyulbuchookau-tang on Global Cerebral Ischemia of the Rats
- Effect of Naenghyo-hwan on Secretion of Airway Mucin and Contractility of Tracheal Smooth Muscle
- Short Term Reaction to Acupuncture Treatment and Adverse Events Following Acupuncture in Korea a Cross-sectional Survey of Patient Reports
- A Clinical Study on the Relationship between Functional Dyspepsia(FD) and Biosignals from Heart Rate Variability(HRV) and Yangdorak Diagnosis
- An Analysis of Tendencies of Studies on Herbal Acupuncture -Focusing on domestic theses since 2001 about anti-inflammation, pain relief and anti-obesity effects, including safety-
- A study on Skin Resistance Variability (SRV) of Woman with Uterine Myoma
- The effect of Kuwonsimsin-hwan on Imunosuppression Induced by Methotrexate in Rat
- The Effects of Gagbyungyunsoo-tanghap Zeungsonbakchul-san(GYZB) Hot Water Extract & Ultra-fine Powder on the Alzheimer's Disease Model
- Inhibitory Effect of Angelica gigias Nakai Extrcact on Nitric Oxide Production in RAW 264.7 Cells
- Effects of Daegeum-eumja, Igwi-tang Sihosogan-san on Gastric Mucosal Lesions Induced by Alcohol, Indomethacin and Burn-stress in Mice
- Damsam-san Inhibits Atherosclerosis through Regulation of Foam Cell Formation and Vascular Smooth Muscle Proliferation
- Acute Toxicity Study on Sagunja-tang(Sijunzi-tang) in ICR Mice
- Combined Treatment of Oriental Herbal Medicine and Prescribed Drugs among Cancer Patients
- Study of Apoptotic Effect on Hydrogen Peroxide-induced Rat PC-12 Cells by Aster tataricus Water Extract
- The Effects of Jiyutang against Gastric and Ileac Mucosal Ulcer Induced by Indomethacin in Mouse
- Acute Stroke in the Elderly Male -Clinical Features,Stroke Subtypes, and Sasang Constitutions-
- more
Recommanded Articles
This website recommended the use the Chrome browser for journal website.