- P-ISSN 1010-0695
- E-ISSN 2288-3339
- Log In/Sign Up
- P-ISSN1010-0695
- E-ISSN2288-3339
Article Detail
Home > Article Detail
Effect of Insamyangyoung-tang on the Skin Barrier Function of Hairless Mice
Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2007, v.28 no.4, pp.18-26
Hae-Jeong,
N.
, &
Yoon-Bum,
K.
(2007). Effect of Insamyangyoung-tang on the Skin Barrier Function of Hairless Mice. Journal of Korean Medicine, 28(4), 18-26.
- Downloaded
- Viewed
Abstract
Objective : To study the effect of the Insamyangyoung-tang (ISYT) extract on the skin barrier function, the skin pH, skin humidity and transepidermal water loss (TEWL) were measured and histological changes were observed in DNCB (2,4-dinitrochloro-benzen)-induced contact dermatitis (CD) hairless mice. Methods : The male hairless mice were divided into three groups. Each group consisted of 15 mice. The normal group which had acetone- olive oil applied. The control group which had intentionally induced CD by DNCB and it was fed normal saline orally. The ISYT group which had intentionally induced CD by DNCB and it was fed ISYT extract orally for 7 days. The three groups were checked 24h, 48h and 72h later after inducing CD, and the skin pH, skin humidity and TEWL were observed. Tissue samples were taken, and damage to the epithelial cell was observed. Statistical analysis was performed by using one way-ANOVA: significance was set at p values less than 5% (p<0.05). Results : ISYTextract efficiently maintained the pH balance, it kept the skin humidity at a normal level, and it inhibited TEWL of the DNCB-induced CD hairless mouse. The damage to the epithelium was decreased and the regeneration power of the skin was increased in the ISYT group. Conclusion : Insamyangyoung-tang has a good effect on the skin barrier function of DNCB induced contact dermatitis hairless mice.
- keywords
- nsamyangyoung-tang, Skin barrier function, Skin pH, Skin humidity, Transepidermal Water Loss, nsamyangyoung-tang, Skin barrier function, Skin pH, Skin humidity, Transepidermal Water Loss
Reference
1
(1999) Ann SK Skin Barrier,
2
(1995) Are Atopics increasing in Korea?,
3
(2002) Changes of the Prevalence and the Allergens of Atopic Dermatitis in Children: In between the years 1992 and 2002,
4
The revision of the Yellow Emperor’s Inner Canon Institute of Chinese medicine 1985,
5
(1998) The Effect of Gamiseungmagalgeun-tang on Allergiccontact dermatitis induced by DNCB in Mice,
6
(2005) The Effect of Yangh- yulsamultanggamibang to Allergic Contact Dermatitis,
7
(2005) The Effect of Sanpung- gosamhwan on Allergic Contact Dermatitis,
8
(2004) Establishment of an atopic dermatitis-like skin model in a hairless mouse by repeated elicitation of contact hypersensitivity that enables to conduct functional analyses of the stratum corneum with various non-invasive biophysical instruments,
9
(2002) Effect of Renshenyangrong-tang in the Specific Immune Response in BALB/c Mice,
10
(1998) Experimental Studies on Anti-tumor and Immunomodulatory Effects of Renshenyangrong-tang,
11
(dermatolclin1990) Factors predisposing to cutaneous irritation,
12
(2006) Transepidermal water loss, serum IgE and B-endorphin as important and independent biological markers for development of itch intensity in atopic dermatitis,
13
(1998) Barrier recovery is impeded at neutral pH, independent of ionic effects: implications for extracellular lipid processing,
14
(2004) The stratum corneum: structure and function in health and disease,
15
(1995) Measurement and Comparison of Hydration and Lipid Levels between Patients with Acne Vulgaris and Patients with Atopic Dermatitis,
16
(dermatology1994) Comparative Measurement of Skin Surface Hydration Using a Hydrometer and Corneometer,
17
(1998) Patterned acquisition of skin barrier function during development,
18
(clinexpdermatol1990) Individual and instrumental variations in irritant patch-test reactions- clinical evaluation and quantification by bioengineering methods,
19
(contactdermatitis1990) Guidelines for water loss A report from the standardization group of the European Society for Contact Dermatitis,
20
The effects of skin moisturizers determined by the measurement of transepidermal water loss Ugeskriff for Leager 1987,
- Downloaded
- Viewed
- 0KCI Citations
- 0WOS Citations
Other articles from this issue
- Sex Differences in Acute Stroke Patients-Clinical Features, Stroke Subtypes, and Sasang Constitutions-
- Circadian Variation of Acute Stroke -Hospital Based Study-
- A Clinical Report of Adult Acute Viral Hepatitis Type A Treated with Herbal Prescriptions
- Effect of Insamyangyoung-tang on the Skin Barrier Function of Hairless Mice
- Effects of Inonotus obliquus Extracts on Immunomodulating Activity
- Coffee Consumption as a Risk Factor of Ischemic Cerebral Infarction in Koreans
- A Clinical Study About Difference Between Recognition of One's own Body Figure and the Real Body Shape
- Analysis of the Relationships Between Sasang Typology, Holland's Vocational Typology, and Myers-Brigg's Types Among Undergraduate Students at the College of Oriental Medicine
- The Clinical Effect of Manipulation of Acupuncture to Shen-Men and Nei-Kuan on Autonomic Nervous Function of Healthy Subjects.
- A Clinical Trial to Assess the Efficacy of Acupuncture on Hot Flashes in Postmenopausal Women
- A Randomized Controlled Trial to Verify Effects of Kuesu Point on Low Back Pain and Accompanied Sciatica
- The Changes of Health Care Utilization and Cause of Outpatients at an Oriental Medicine Hospital
- Effect of Amygdalin from Armeniacae Semen on Ion Currents Changed by Lipopolysaccharide in Rat Periaqueductal Gray Neurons
- Effect of Aralia Cordata Pharmacopuncture on Cartilage Protection and Apoptosis Inhibition In Vitro and in Collagenased-induced Arthritis Rabbit Model
- Analgesic and Anti-Inflammatory Effect of Scutellaria baicalensis
- The Anti-obesity Effects of Gambi-hwan Extract on Obese Rats Induced by High-fat Diet through the Expression of UCP-1 and PPARδ
- Effect of Cinnamomum cassia on Cartilage Protection in Rabbit and Human Articular Cartilage
- Effects of Uncaria rhynchophylla Extracts on Differentiation and Bone Mineralized Formation in Human Osteoblast-like SaOS-2 cells
- A Clinical Study of Korean Medical Treatment and Korean and Western Medical Treatment on Acute Ischemic Stroke Patients
- Two Cases of Endometrial Cancer Treated with Palliative Herbal Medication Hangam-dan (HAD)
- more
Recommanded Articles
This website recommended the use the Chrome browser for journal website.