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Journal of the Korean Association of Oral and Maxillofacial Surgeons

  • P-ISSN2234-7550
  • E-ISSN2234-5930
  • SCOPUS, KCI, ESCI

만성경화성 하악골골수염의 임상적검토 - 외측피질골제거술 및 동주요법(국소화학요법) 병용의 증례에 관하여 -

Clinical observations on mandibular chronic osteomyelitis - Combination therapy of decortication and intra-arterial infusion chemotherapy -

Journal of the Korean Association of Oral and Maxillofacial Surgeons / Journal of the Korean Association of Oral and Maxillofacial Surgeons, (P)2234-7550; (E)2234-5930
2008, v.34 no.3, pp.350-354
구로이와 이치로 (일본 아이치학원대학)
마츄라 히로아키 (일본 아이치학원대학)
아베 아스시 (일본 아이치학원대학)
가토 무지오 (일본 아이치학원대학)
아리지 요시코 (일본 아이치학원대학)
쿠리타 케니치 (일본 아이치학원대학)

Abstract

Mandibular chronic osteomyelitis with diffuse osteosclerosis is recognized as an intractable infectious disease. We emplyed decortication and intra-arterial infusion of antibiotics in 6 cases. Decortication on the affected mandible was performed with retrocatherization to the superficial temporal artery of affected side under general anesthesia. Antibiotics, IPM/CS or FOMX was used through the artery for 4-11 days. In addition, we administered FOMX, PIPC intravenously for 8-17 days. CT and MRI were taken postoperatively. The postoperative follow-up period ranged from 1 year and 6 months to 2 years and 5 months. Postoperative MR showed that bone marrow signal was recovered to approximately normal in 4 cases. High signal area of bone marrow and osteosclerosis image remained in 2 cases, but showed improvement. The results were satisfactory without recurrence in all of 6 cases.

keywords
Chronic osteomyelitis, Diffuse osteosclerosis, Intra-arterial infusion, Antibiotic, Decortication

Journal of the Korean Association of Oral and Maxillofacial Surgeons