Journal of the Korean Association of Oral and Maxillofacial Surgeons
- P-ISSN2234-7550
- E-ISSN2234-5930
- SCOPUS, KCI, ESCI
ISSN : 2234-7550
진성 다혈구증 환자에서 진행된 구강암의 치료 : 증례보고
A POLYCYTHEMIA VERA PATIENT IN ADVANCED ORAL CAVITY CANCER TREATMENT : REPORT OF A CASE
차인호 (연세대학교)
김형준 (연세대학교)
남웅 (연세대학교)
최세경 (연세대학교)
최종명 (연세대학교)
Abstract
Polycythemia vera is one type of myeloproliferative disorder which occurs due to the clonal proliferation of hematopoietic stem cell related to theproduction of leukocyte and megakaryocyte which produces a little less than erythrocyte. Polycythemia vera has a peak incidence in the sixth decadeof life with males affected slightly more frequently than females. Vasquez first described polycythemia vera as an autonomous erythrocytosis in 1892, and a further description, delineation of the disease processand a complete course outline were made in 1899, 1903 and 1938, respectively. Symptoms include pruritus, tinnitus, vertigo, gastrointestinal (GI) pain, and bleeding gums. Hyperuricemia and hyperuricosuria are present in about40% of these patients. Complications are hemorrhage, thrombosis, post-polycythemic myeloid metaplasia, and leukemic transformation. In case of surgery, complicationssuch as hemorrahge and thrombosis are highly likable to happen. We report a case of preoperative and postoperative of a 63-year-old male, who was diagnosed as oral cavity cancer in the mouth floor, with knownhistory of hypertension and polycythemia vera. We considered that conservative management would be an advisable treatment for patients withuncontrolled systemic disease
- keywords
- Polycythemia vera, Oral cancer, Surgery
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