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ACOMS+ 및 학술지 리포지터리 설명회

  • 한국과학기술정보연구원(KISTI) 서울분원 대회의실(별관 3층)
  • 2024년 07월 03일(수) 13:30
 

Journal of the Korean Association of Oral and Maxillofacial Surgeons

  • P-ISSN2234-7550
  • E-ISSN2234-5930
  • SCOPUS, KCI, ESCI

Treatment outcomes and prognostic factors in oral tongue cancer: a 20-year retrospective study at the National Cancer Center, South Korea

Journal of the Korean Association of Oral and Maxillofacial Surgeons / Journal of the Korean Association of Oral and Maxillofacial Surgeons, (P)2234-7550; (E)2234-5930
2022, v.48 no.4, pp.192-200
https://doi.org/10.5125/jkaoms.2022.48.4.192
Kim Min-Gyeong (Oral Oncology Clinic, Research Institute and Hospital, National Cancer Center, Goyang, Korea)
Choi Yong-Seok (Oral Oncology Clinic, Research Institute and Hospital, National Cancer Center, Goyang, Korea)
Youn Suk Min (Oral Oncology Clinic, Research Institute and Hospital, National Cancer Center, Goyang, Korea)
Ko Jae-Hee (Oral Oncology Clinic, Research Institute and Hospital, National Cancer Center, Goyang, Korea)
Oh Hyun Jun (Oral Oncology Clinic, Research Institute and Hospital, National Cancer Center, Goyang, Korea)
Lee Jong-Ho (Oral Oncology Clinic, Research Institute and Hospital, National Cancer Center, Goyang, KoreaDepartment of Oral and Maxillofacial Surgery, Seoul National University Dental Hospital, Seoul, KoreaOral Cancer Center, Seoul National University Dental Hospital, Seoul, Korea)
Park Joo-Yong (Oral Oncology Clinic, Research Institute and Hospital, National Cancer Center, Goyang, Korea)
최성원 (국립암센터국제암대학원대학교)

Abstract

Objectives: This study aimed to analyze the treatment outcomes and to evaluate the clinicopathological prognostic factors of oral tongue cancer. Patients and Methods: We retrospectively analyzed treatment results and prognostic factors in 205 patients with oral tongue squamous cell carcinoma who were admitted to the National Cancer Center, South Korea, between January 2001 and December 2020. The patients were treated with surgery and postoperative, definitive radiotherapy (RT) or chemoradiotherapy (CRT). Results: Eighteen patients (8.8%) were treated with curative RT or CRT, while the rest (91.2%) were treated with surgery with or without postoperative RT or CRT. The median follow-up period was 30 months (range, 0-234 months). The 5-year overall survival (OS) and 5-year disease-free survival (DFS) were 72% and 63%, respectively. Multivariate analysis revealed that a positive neck nodal status (N1, N2-3) was significantly associated with poorer 5-year OS and DFS, while perineural invasion was associated with poorer 5-year DFS. Conclusion: Cervical metastasis and perineural invasion are significant prognostic predictors, and combination treatments are necessary for improving OS and DFS in patients with these factors.

keywords
Tongue, Oral cancer, Treatment outcome, Prognostic factors

Journal of the Korean Association of Oral and Maxillofacial Surgeons