ACOMS+ 및 학술지 리포지터리 설명회

  • 한국과학기술정보연구원(KISTI) 서울분원 대회의실(별관 3층)
  • 2024년 07월 03일(수) 13:30
사전등록 바로가기
 

논문 상세

Home > 논문 상세
  • P-ISSN 1010-0695
  • E-ISSN 2288-3339

이전

27권 2호
Share

Effects of Insamsansa-eum (Renshenshanzha-yin) on Hypercholesterolemia and Analysis of Its Effects according to the Pattern Identification

대한한의학회지 / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2006, v.27 no.2, pp.253-261
Seong Uk Park (Kyung-Hee University)
Chang Nam Ko (Kyung-Hee University)
Woo Sang Jung (Kyung-Hee University)
Sang Kwan Moon (Kyung-Hee University)
Ki Ho Cho (Kyung-Hee University)
Young Suk Kim (Kyung-Hee University)
Hyung Sup Bae (Kyung-Hee University)
Seong, U. P. , Chang, N. K. , Woo, S. J. , Sang, K. M. , Ki, H. C. , Young, S. K. , & Hyung, S. B. (2006). . 대한한의학회지, 27(2), 253-261.
  • 다운로드 수
  • 조회수

Abstract

Backgrounds: Hyperlipidemia is a major cause of cardiovascular disease (CVD). Lowering serum cholesterol levels could reduce the risk of CVD. Insamsansa-eum (Renshenshanzha-yin, ISE), composed of Ginseng Radix and Crataegii Fructus, is a new medicine developed to treat hyperlipidemia and CVD. Objectives: In this study, we intended to explore the clinical effects of ISE on patients with hypercholesterolemia, and moreover we also compared its effects according to the pattern identification. Methods: Subjects were administered ISE with the dose of 600 mg three times a day for 4 weeks. Patterns of subjects were identified with diagnostic scoring system for Yin-Yang and the condition of Excess-Deficiency before treatment. Serum lipids were measured at baseline and after 4 weeks of medication. Results: ISE lowered total cholesterol (TC), triglyceride (TG), total lipid (TL), phospholipid (PL) and low density lipoprotein cholesterol (LDL) significantly. Compared with the data of our previous study, it was less effective than Atorvastatin but showed equal lipids-lowering effect to Chunghyul-dan (Qingxue-dan, CHD). In Yang pattern group, ISE was less effective in lowering TG and LDL than it was in not-Yang-not-Yin pattern group. On safety assessment, there was no adverse effect, hepatic or renal toxicity. Conclusions: We suggest that ISE is a safe and useful herbal medicine for hypercholesterolemia, and moreover it could be more useful when it is used for patients with not Yang pattern.

keywords
Insamsansa-eum (Renshenshanzha-yin, ISE), Hypercholesterolemia, Pattern identification


  • 다운로드 수
  • 조회수
  • 0KCI 피인용수
  • 0WOS 피인용수

권호 내 다른 논문

추천 논문

상단으로 이동

권호 목록

소개

규정 및 지침

게시판

대한한의학회지

  학술지 홈페이지 이용 환경은   크롬 브라우저 사용을 권장합니다.

대한한의학회지

논문 투고 OA 정책