E-ISSN : 2733-4538
This study was conducted to investigate the effect of posterolateral amygdala(PLA) lesion on chronic ulcer induced by activity-stress(A-S) procedure. The PLA is suggested to play an inhibitory role in stress-induced stomach ulcer. Albino rats were used as subjects in the study and they were divided into two groups : PLA-lesioned group and sham-operated control group. After 3 days of adaptation, they had a limited feeding schedule of one hour per day, and except for the feeding time they were always allowed to access to the activity wheel for 7 days. Results showed that PLA-lesioned group had a tendency of increasing ulcer in the A-S procedure, which was indicated by the increased total length of ulcer. Running activity, weight loss and food/water intake, which are behavioral indices, showed little difference between the two groups. Taken together, the results suggest that the PLA lesion plays an facilitatory role in activity-stress as well as in traditional restraint procedure.