Abstract

This study investigated the impact of psychological conflict induced by the inconsistent feedback of coping behavior on the physiological, behavioral change and ulceration, and examined the effects of psychotropic agents on the coping behavior and ulceration which were induced by the conflict-stress conditions. Results of the experiments were as follow. The experimental animal showed a significant reduction in coping behavior, body weight loss, and severe ulceration compared to yoked-control animals. The acute effects of psychotropic drugs were not found in terms of coping behavior reduction, body weight loss, and ulceration. However, the chlorpromazine treatment group suggest the tendency to relieve ulceration. The chronic drug effect showed that chlorpromazine prevent the reduction of coping behavior under the conflict condition and amitriptyline relieve the ulceration. Chlorpromazine, chlordiazepoxide treatment groups suggest the tendency to relieve ulceration.