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  • 한국과학기술정보연구원(KISTI) 서울분원 대회의실(별관 3층)
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  • P-ISSN2233-4203
  • E-ISSN2093-8950
  • ESCI, SCOPUS, KCI

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  • P-ISSN 2233-4203
  • E-ISSN 2093-8950

Identification of Ceftiofur Oxidation Products by High-Performance Liquid Chromatography/Electrospray Ionization/Tandem Mass Spectrometry

Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2011, v.2 no.1, pp.16-19
https://doi.org/10.5478/MSL.2011.2.1.016
Young-Hee Lim (LG Chem)
Deok-Hie Park (LG Chem)
Yeu Young Youn (LG Chem)
Kyung Hoon Kim (LG Chem)
Hye-Sung Cho (LG Chem)
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Abstract

Oxidation products of ceftiofur were formed in hydrogen peroxide solution. The structures of the ceftiofur oxidationproducts were characterized by high-performance liquid chromatography/electrospray ionization/tandem mass spectrometry(HPLC/ESI/MS/MS). The products were identified as compounds oxidized at the sulfur of a cephem ring. For further analysis,an experiment was performed using O18-labeled hydrogen peroxide. Results of the density-functional calculations for six possibleoxidation products were in good agreement with the experimental results.

keywords
Ceftiofur, Oxidation, ESI, Density-functional Calculation, Hydrogen Bonding


참고문헌

1

Ritter, L. WHO Food-Additives Series.

2

Jaclan, P. S. (1989). . J. Agric. Food Chem, 37, 1112-.

3

Koshy, K. T.. (1997). . J. Pharmaceut. Sci, 86, 389-.

4

Keeveer, J. (1998). . J. Chromatogr. A, 794, 57-.

5

Heller, D. N.. (1998). . Rapid Commun. Mass Spectrom, 12, 2031-.

6

Daeseleire, E. (2000). . Rapid Commun. Mass Spectrom, 14, 1404-.

7

Holstege, D. M. (2002). . J. Agric. Food Chem, 50, 406-.

8

Berendsen, B. J. A.. (2009). . J. Chromatogr. A, 1216, 8177-.

9

Kantiani, L.. (2009). . Anal. Chem, 81, 4285-.

10

Sunkara, G. (1999). . J. Pharm. Pharmacol, 51, 249-.

11

Tanaka, H. (1996). . Tetrahedron, 52, 2343-.

12

Mangia, A.. (1978). . Synthesis, 361, -.

13

(2010). DMol3 Quantum Mechanical Program and Materials Studio 5.5 Molecular Modeling System:Accelrys Inc..

14

Becke, A. D. (1998). . Phys. Rev. A, 38, 3098-.

15

Perdew, J. P. (1992). . Wang, Y. Phys. Rev. B, 45, 13244-.

16

Delley, B. J.. (1990). . Chem. Phys, 92, 508-.

투고일Submission Date
2011-02-03
수정일Revised Date
2011-03-07
게재확정일Accepted Date
2011-03-07
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