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Abstract

Objectives: To review the concept of Moebius syndrome. Methods: Literature search was done to study definition, epidemiology, pathophysiology, clinical feature, and treatment of Moebius syndrome. Pubmed, RISS, Google scholarship and uptodate scholastic were used in the research. Search words were 'Moebius syndrome', 'treatment of Moebius syndrome'. Only English and Korean studies were assessed. Results: Moebius syndrome is rare disease characterized by nonprogressive congenital uni- or bi-lateral facial (VII cranial nerve) and abducens (VI cranial nerve) palsy. This facial palsy is found across the world, and its incidence is approximately 1 per 250,000. Moebius is diagnosed by clinical features. Facial palsy, eye abduction problem, limb deformities, global cerebral nerve impairment can be shown. Rehabilitation, smile surgery, and acupuncture can be used to treat this. Conclusion: Moebius syndrome's epidemiology, pathogenesis, treatment is still not fully revealed. It is known to be a congenital disease which didn't have exact treatment except surgery. But, it needs further study about exact treatment, diagnosis, and pathogenesis.

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Objectives: Excessive accumulation of fat on specific region, regarded as localized fat, is one of the serious problems and well-known risk factors of health. Recently, an interest in health and aesthetics is growing by treating lipolytic injection. Polygonatum sibiricum Rehd (PS) has been known to have anti-oxidant, -aging and -atherosclerotic effects. In this study, we investigated the lipolytic effects of PS pharmacopuncture in obese mice. Methods: Male C57BL/6J mice was fed with high fat diet to induce obesity for 12 weeks. PS pharmacopuncture was dissolved in saline by adjusting pH 7. 100 𝜇L of PS pharmacopunture was injected subcutaneously into the left side inguinal fat pad, while saline was injected into the right side inguinal fat pad in mice as self-control. Samples were treated 3 times per weeks for 2 weeks. Results: PS pharmacopunture significantly decreased the inguinal fat weight compared to left side inguinal fat pad. Decrease rate of PS pharmacopuncture was about 21%. In addition, the diameter of adipocyte in inguinal fat tissues was significantly reduced by 17% compared to saline-injected side. There was no sign of toxicity through whole experiments. Conclusion: The present study indiates that PS pharmacopunture could be a material derived from natural herb as a lipolytic injection for decreasing localized fat.

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경혈과 경락학설은 침의 치료 효과를 설명하고 최선의 침 치료 전략을 세우기 위해 이용되어왔다. 이번 연구를 통해 요통 환자를 대상으로 한 무작위 대조군 임상 연구에서 요통을 치료하기 위해 사용된 경혈의 빈도를 알아보았다. PUMBED 데이터베이스를 통해 요통 환자를 대상으로 manual acupuncture나 electro-acupuncture를 사용한 논문을 분석했다. 총 664편의 논문이 검색되었으며, 그 중 62편의 논문을 분석 결과에 따르면 신수, 위중, 대장수, 곤륜, 환도, 아시혈, 관원수, 양릉천, 기해수, 요양관이었으며, 태계혈이 함께 조합되어 사용되었다. 이를 통해 요통에 대한 침 치료효과를 밝히기 위한 이전의 연구들에서 족태양방광경의 경혈들이 주로 사용된 것, 그리고 근위와 원위의 경혈이 사용된 것을 알 수 있다. 추후 연구를 통해 경혈과 치료 효과 간의 상관 관계를 밝히고 경혈을 선정하고 조합하는 원리에 대한 가이드라인을 제시하기 위해서는 치료 효과에 대한 정량적인 분석 방법과 이용한 경혈에 대한 자세한 보고가 필수적이다.

Abstract

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Abstract

Objectives: The purpose of this study is to investigate the effect of ultrasound therapy on left knee pain and instability diagnosed with Baker's cyst in a 25-year-old male patient. Methods: Patient was treated with Radio frequency ablation treatment on left knee from Naeseulan (EX-LE4) to Wijoong (BL40). The effect of radio frequency ablation was assessed by Visual Analog Scale (VAS), Western Ontario and McMaster Universities (WOMAC) and Euro Qol-5 Dimension Index (EQ-5D Index). The treatment was executed one time a day everyday form May 28th to June 1st of 2020. Patient was observed from May 26th to June 1st. Results: After five sessions of radio frequency ablation, VAS of left posterior knee pain was improved while no improvement was discovered at left medial knee. In Korean WOMAC scale, only subscale of weight bearing and walking around plain were improved. EQ-5D did not show any improvement. Conclusion: The results suggest that radio frequency ablation treatment can be a valuable option in treating knee pain and daily living function. Further study seems to be needed based on long-term intervention.