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  • 한국과학기술정보연구원(KISTI) 서울분원 대회의실(별관 3층)
  • 2024년 07월 03일(수) 13:30
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ISSN : 0376-4672

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60권 7호

코로나바이러스(SARS-CoV-2)에 대한 구강 양치액의 효과: 주제 범위 문헌고찰

A scoping review on the effectiveness of mouth rinse against SARS-CoV-2

이주영 (연세대학교 예방치과학교실, BK21플러스 통합구강생명과학 사업단)
김효정 (연세대학교 예방치과학교실, BK21플러스 통합구강생명과학 사업단)
정회인 (연세대학교)
김백일 (연세대학교)
대한치과의사협회지 / The Journal of the Korean Dental Association, (P)0376-4672; (E)2713-7961
2022, v.60 no.7, pp.422-435
https://doi.org/10.22974/jkda.2022.60.7.002
이주영, 김효정, 정회인, & 김백일. (2022). 코로나바이러스(SARS-CoV-2)에 대한 구강 양치액의 효과: 주제 범위 문헌고찰. 대한치과의사협회지, 60(7), 422-435, https://doi.org/10.22974/jkda.2022.60.7.002

Abstract

Although studies reporting the efficacy of mouth rinse against SARS-CoV-2 have been continuously published, it is chal lenging to select literature through qualitative meta-synthesis or quality assessment of the study. Therefore, this study aims to systematically review the efficacy of mouth rinse against SARS-CoV-2 using the scoping review method and to provide the latest information. Literature search on electronic databases (PubMed, Scopus, and Cochrane Trials) was conducted. After establishing liter ature inclusion and exclusion criteria, two independent researchers were selected literatures. Of the 15 articles were included in this scoping review, 11 were in vitro studies, and four were in vivo studies. The ingredients tested in these studies were povidone-iodine, chlorhexidine, hydrogen peroxide, essential oils, and qua ternary ammonium compounds, and they showed various efficacy against SARS-CoV-2. Despite the relatively limited evidence from the included studies, the use of mouth rinse has the potential to reduce the viral load of SARS-CoV-2. In particular, povidone-iodine is expected to be the most effective against SARS-CoV-2, given the evidence so far.

keywords
COVID-19, mouth rinse, povidone-iodine, SARS-CoV-2, virus

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