- P-ISSN 1010-0695
- E-ISSN 2288-3339
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- P-ISSN1010-0695
- E-ISSN2288-3339
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Study on the Relationship between Iris Constitution and Apolipoprotein E Gene Polymorphism
Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2003, v.24 no.4, pp.25-33
Sung-Do,
K.
, Woo-Jun,
H.
, Kyung-A,
K.
, Kyung-Sik,
K.
, Ho-Sub,
L.
, Jong-Uk,
K.
, Sung-Yong,
C.
, &
Kyong-Son,
J.
(2003). Study on the Relationship between Iris Constitution and Apolipoprotein E Gene Polymorphism. Journal of Korean Medicine, 24(4), 25-33.
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Abstract
Iridology, one of complementary and alternative medicine (CAM), is the diagnosis of the medical conditions through noting irregularities of the pigmentation in the iris. Iridological constitution has a strong familial aggregation and is implicated in heredity. Apolipoprotein E (apoE) gene polymorphism is one of the most well studied genetic markers of vascular disease. Then I investigated the relationship between iridological constitution and apoE polymorphism. I classified 87 hypertensives patients with family history of cerebral infarction and 79 controls according to Iris constitution, and determined apoE genotype. Neurogenic type in hypertensives was 32.2% compared with 16.5% in controls (P<0.001). No differences in the apoE genotypes frequencies were observed in patients compared with that in controls ( 2=0.726, df=2, P=0.696). However, in population with 3/ 4 genotype, the frequency of neurogenic constitution was significantly higher in hypertensives than in controls (60% vs. 0%) ( 2=5.265, df=1, P=0.022). These results could be implied that apo E 3/ 4 genotype and neurogenic Iris constitution are risk factors for hypertension.
- keywords
- Iridology, Apolipoprotein E, Hypertension, Polymorphism, Iridology, Apolipoprotein E, Hypertension, Polymorphism
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