- P-ISSN 1010-0695
- E-ISSN 2288-3339
- 권한신청
- P-ISSN1010-0695
- E-ISSN2288-3339
논문 상세
Home > 논문 상세
The Inhibition Effect of Water Extract of Acanthopanax senticousus Harms Roots on the 5-HT Induced Vasocontraction in Rat
대한한의학회지 / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2003, v.24 no.4, pp.82-86
(경희대학교)
(경희대학교)
(경희대학교)
(경희대학교)
(경희대학교)
(경희대학교)
(경희대학교)
Hyung-Hwan,
K.
,
Duk-Kyun,
A.
,
Chang-Soo,
Y.
,
&
Ho-Young,
C.
(2003). . 대한한의학회지, 24(4), 82-86.
- 다운로드 수
- 조회수
Abstract
Objective : We have examined the inhibition of 5-Hydroxytryptamine (5-HT) induced vasocontraction to the water extract of Acanthopanax senticusus Harms. roots (ASR) on rat thoracic aorta and mesenteric artery with and without endothelium.Methods : Segments of thoracic aorta and mesenteric artery obtained from rats immediately after delivery were mounted in organ baths superfused on a polygraph.Results : We found that the thoracic aorta segments responded to the water extract of ASR with a dose-dependent and concentration-dependent vasorelaxation. 5-HT produced a concentration-dependent contraction of the thoracic aorta and mesenteric artery. At high concentration, ASR, the inhibition response were 93.7% (Jang-su), 93.5% (Heok-ryong-kang-sung), 92.8% (Back-doo mountain), and 83.5% (Yeon-byun) of the maximum 5-HT induced contraction. At high concentration ASR, the relaxational response at thoracic aorta and mesenteric artery with endothelium were 95.2% and 94.6%. without were 93.5% and 92.5% of the maximum 5-HT induced contraction.Conclusions : In conclusion, the effect of water extract of ASR had potent inhibition at 5-HT and the effect of ASR in isolated thoracic aorta and mesenteric artery showed dose-dependent inhibition but endothelium-independent response.
- keywords
- Acanthopanax senticosus Harms, 5-Hydroxytryptamine, thoracic aorta, mesenteric artery., Acanthopanax senticosus Harms, 5-Hydroxytryptamine, thoracic aorta, mesenteric artery.
- 다운로드 수
- 조회수
- 0KCI 피인용수
- 0WOS 피인용수
권호 내 다른 논문
- The Relative Risk Assessment of Leptin for Stroke in Korea
- Correlation Among Obesity Factors in Stroke in Korea
- Effect of TongBiYeum(TBY) on the Fatty Liver
- Risk Assessment of Smoking for Ischemic Stroke in Koreans
- Study on the Relationship between Iris Constitution and Apolipoprotein E Gene Polymorphism
- Modulation of Corydalis tuber on Glycine-induced Ion Current in Acutely Dissociated Rat Periaqueductal Gray Neuron
- Effect of Drynariae Rhizoma on the Proliferation of Human Bone Cells
- Effect of TongbBiEum(TBE) on Hyperlipidemia Induced by a Sucrose-rich Diet
- The Effect of a Cooperative System of Oriental and Western Medicine in the Treatment of Allergic Rhinitis
- Recovery Effects from Oxidative Cell Damage by So-Hap-Hyang-Won on Bovine Aortic Endothelial Cells(BAEC)
- The Inhibition Effect of Water Extract of Acanthopanax senticousus Harms Roots on the 5-HT Induced Vasocontraction in Rat
- The Effect of Rheum palmatum L. and Rheum undulatum L. on Rat Thoracic Aorta and Abdominal Aorta
- Incomplete Relationship between Dominant Power of Electrogastrography and Gastric Myoelectrical Activity in patients with Functional Dyspepsia
- Study on Individual and Combined Relationship of Angiotensin Converting Enzyme,Apolipoprotein E and Angiotensinogen Genes Polymorphism in Patients with Ischemic Cerebrovascular Disease
- Study on the Relationship between Polymorphism in Apolipoprotein E Gene and Korean Ischemic Cerebrovascular Disease Patients
- Effect of Samul-tang(Siwu-tang)on Procollagen Synthesis in Cultured Murine Hepatic Non-parenchymal Cells
- Acupuncture Suppresses Intrastriatal Hemorrhage-Induced Neuronal Cell Death and Proliferation in Rats
- The Effects of Live Leech(Hirudo Medicinalis)Therapy on Diabetic Foot : a Clinical Case Report
- A Clinical Study of Oriental Medical Treatment on a Patient with Polyneuropathy
- Clinical Observation on Oculomotor Nerve Palsy Treated by Moxibustion
- more
추천 논문
학술지 홈페이지 이용 환경은 크롬 브라우저 사용을 권장합니다.