- P-ISSN 1010-0695
- E-ISSN 2288-3339
- Apply for Authority
- P-ISSN1010-0695
- E-ISSN2288-3339
Article Detail
Home > Article Detail
Effect of Mahuang on Heart Rate Variability in Adults: a Double-Blind, Placebo-Controlled, Randomized Trial
Journal of Korean Medicine / Journal of Korean Medicine, (P)1010-0695; (E)2288-3339
2007, v.28 no.1, pp.105-116
&
(2007). Effect of Mahuang on Heart Rate Variability in Adults: a Double-Blind, Placebo-Controlled, Randomized Trial. Journal of Korean Medicine, 28(1), 105-116.
- Downloaded
- Viewed
Abstract
Objectives: Mahuang (Ephedra sinica), well known as an herbal medicine in the East and West, contains a relatively high percentage of ephedrine known as sympathomimetic alkaloid. We investigated the effects of Mahuang on sympathetic nervous system with heart rate variety (HRV). Time and frequency domain analysis of HRV is a noninvasive technique capable of providing information on autonomic modulation of the sinus node. Methods: We investigated 57 healthy volunteers consisting of 37 subjects in the Mahuang group and 20 subjects in the placebo group. Study form was a randomized, placebo-controlled, double-blind clinical trial. The 37 subjects in the Mahuang group took 3 Mahuang capsules (1 capsule equivalent to 2g herb Mahuang) twice a day at 10 a.m. and 2 p.m., while the 20 subjects in the placebo group took 3 placebo-capsules filled with glutinous rice powder at the same times. Mahuang medicine and placebo medicine were made into opaque capsules. We measured HRV at 3 p.m. 1 or 2 days before medication and at 3 p.m. after medication. Results: Mean-RR and SDNN of the Mahuang group significantly decreased compared with that of the placebo group, but the heart rate of the Mahuang group significantly increased compared with the placebo. HRV-Index, RMSSD and SDSD of the Mahuang group significantly decreased compared with that of the placebo group, but PNN50 of the Mahuang group significantly increased compared with placebo. Ln(TP), Ln(VLF), Ln(LF) and Ln(HF) of the Mahuang group significantly decreased compared with those of the placebo group. There were no significant differences in normalized LF, normalized HF and LF/HF ratio between the Mahuang and placebo groups. Conclusion: The results suggest that Mahuang in healthy adults tends to reduce the autonomic nervous system within the normal range.
- keywords
- Ephedra, Mahuang, heart rate variability (HRV), clinical trial, herbal medicine, Ephedra, Mahuang, heart rate variability (HRV), clinical trial, herbal medicine
- Downloaded
- Viewed
- 0KCI Citations
- 0WOS Citations
Other articles from this issue
- A Reciew on Herbal Medicinal Products Associated with Toxic Events in Korea
- Effectiveness of Bee Venom Acupuncture on Shoulder Pain after stroke
- A Comparative study on Distinction of Patients with Stroke in the Case of the First Attack and Recurrence
- Analysis of 363 Consecutive Patients with Acute Ischemic Stroke from the Hanbang Stroke Registry
- Midterm Assessment on Forecasting Study of Korean Traditional Medicine
- Association between Genetic Polymorphisms of the CYP2C19,CYP2D6 and Types of Sasang Constitutional Medicine
- Effects of Mahuang for Weight Loss in Healthy Adults: A Double-Blind, Controlled, Randomized, Clinical Trial
- Economic Evaluation of Eastern, Western and Collaborative Treatment for Patients with Frozen Soulder Pain
- Comparison of Therapeutic Effects on Carpal Tunnel Syndrome between Oriental and Western Medicine
- Review on Teaching Traditional Korean Medical Students with English Medical Journals
- Effect of Mahuang on Heart Rate Variability in Adults: a Double-Blind, Placebo-Controlled, Randomized Trial
- Assessment on Forecasting Study of Traditional Chinese Medicine(1990-2010)
- Differences Between Facial Skin Temperature of the Paralyzed Side and Those of the Normal Side in Bell's Palsy Patients
- Studies on the Antioxidant Effects of Carthami Flos Extract
- Studies on the Antioxidant Effects of Mori Folium Extract
- A Study on VDT Syndrome by Sasang Constitution of High School in Su-won City
- A Study on Recognition by Korean Medicine Practitioners of Postpartum Disease and Treatments
- Effects of Jiyutang on DSS-induced Colitis of the Mouse
- Protective Effect of Red Ginseng and Paeonia radix against Nitric Oxide-Induced Apoptosis in Human Neuroblastoma SK-N-MC cells
- Effects of Rhizoma Arisaematis on Lipid and Glucose Metabolism and Hisstochemical Changes of Rats Fed High Fat Diet
- A Preliminary Study on the Inhibitory Effect of Chunghyul-dan on Stroke Recurrence in Patients with Small Vessel Disease
- Effects of Iksujisundan on Renal function, Peroxynitrite Scavenging Activity and Polyol in Streptozotocin-induced Diabetic Rats
- A Study on the Relationship among Hair Tissue Mineral Analysis Autonomic Functions and Obesity
- more
Recommanded Articles
This website recommended the use the Chrome browser for journal website.